Abstract：
OBJECTIVE: To investigate the diagnostic performance and complication rates of percutaneous transthoracic CT-guided coaxial core needle biopsy (PTCNB) in persistent consolidations and evaluate its safety in routine clinical practice.
METHODS: A total of 685 patients (404 males, 281 females) underwent PTCNB with coaxial core technique for persisted consolidation were reviewed in this study. According to histopathological and microbiological analysis, the results of biopsy specimens were categorized as follows: malignant, specific benign, non-specific benign and non-diagnostic. The final diagnosis was established through surgical resection or clinicoradiological follow-up for at least 12 months following biopsy. Diagnostic yield of PTCNB was defined as the percentage of the true diagnosis from biopsy as malignant and specific benign lesions.
RESULTS: With respect to the final diagnosis, 54 (54/685; 7.88%) cases were obtained by surgery and the remaining were by follow-up. The total accuracy, sensitivity, specificity of PTCNB for malignancy diagnosis was 94.45%, 84.87%, 100%, respectively. Diagnostic yield of PTCNB was 66.28%. Compared to lesions smaller than 3 cm, higher diagnostic yield (70.89%), lower complication incidence (38.22%) and shorter procedure time (8.78 min) were observed in lesions ≥ 3 cm group.
CONCLUSIONS: PTCNB in persistent consolidation is a safe and effective procedure, which provide relatively high diagnostic yield and acceptable complication, especially in size over 3 cm lesions.
UNASSIGNED: CT-guided coaxial needle biopsy for pulmonary consolidation is a safe and effective procedure. The coaxial needle biopsy yielded high diagnostic rates and low complication rates (including pneumothorax and intrapulmonary hemorrhage), especially in larger lesions.
METHODS: A total of 685 patients (404 males, 281 females) underwent PTCNB with coaxial core technique for persisted consolidation were reviewed in this study. According to histopathological and microbiological analysis, the results of biopsy specimens were categorized as follows: malignant, specific benign, non-specific benign and non-diagnostic. The final diagnosis was established through surgical resection or clinicoradiological follow-up for at least 12 months following biopsy. Diagnostic yield of PTCNB was defined as the percentage of the true diagnosis from biopsy as malignant and specific benign lesions.
RESULTS: With respect to the final diagnosis, 54 (54/685; 7.88%) cases were obtained by surgery and the remaining were by follow-up. The total accuracy, sensitivity, specificity of PTCNB for malignancy diagnosis was 94.45%, 84.87%, 100%, respectively. Diagnostic yield of PTCNB was 66.28%. Compared to lesions smaller than 3 cm, higher diagnostic yield (70.89%), lower complication incidence (38.22%) and shorter procedure time (8.78 min) were observed in lesions ≥ 3 cm group.
CONCLUSIONS: PTCNB in persistent consolidation is a safe and effective procedure, which provide relatively high diagnostic yield and acceptable complication, especially in size over 3 cm lesions.
UNASSIGNED: CT-guided coaxial needle biopsy for pulmonary consolidation is a safe and effective procedure. The coaxial needle biopsy yielded high diagnostic rates and low complication rates (including pneumothorax and intrapulmonary hemorrhage), especially in larger lesions.
摘要：
目的：探讨经皮经胸CT引导同轴芯针穿刺活检(PTCNB)在持续性合并中的诊断表现和并发症发生率，并评价其在常规临床实践中的安全性。
方法：共685例患者（男性404例，在这项研究中，对281名女性）进行了同轴核心技术的PTCNB治疗。根据组织病理学和微生物学分析，活检标本的结果分类如下：恶性，特异性良性，非特异性良性和非诊断性。最终诊断是通过活检后至少12个月的手术切除或临床放射随访确定的。PTCNB的诊断率定义为活检为恶性和特定良性病变的真实诊断百分比。
结果：关于最终诊断，54例（54/685；7.88%）通过手术获得，其余通过随访获得。总精度，灵敏度,PTCNB对恶性肿瘤诊断的特异性为94.45%,84.87%,100%,分别。PTCNB的诊断率为66.28%。与小于3厘米的病变相比，更高的诊断率（70.89%），病灶≥3cm组并发症发生率较低(38.22%),手术时间较短(8.78min)。
结论：PTCNB在持续巩固中是一种安全有效的手术，提供相对较高的诊断率和可接受的并发症，特别是大小超过3厘米的病变。
■CT引导同轴穿刺活检肺实变是一种安全有效的手术。同轴穿刺活检的诊断率高，并发症发生率低（包括气胸和肺内出血）。尤其是较大的病变。
方法：共685例患者（男性404例，在这项研究中，对281名女性）进行了同轴核心技术的PTCNB治疗。根据组织病理学和微生物学分析，活检标本的结果分类如下：恶性，特异性良性，非特异性良性和非诊断性。最终诊断是通过活检后至少12个月的手术切除或临床放射随访确定的。PTCNB的诊断率定义为活检为恶性和特定良性病变的真实诊断百分比。
结果：关于最终诊断，54例（54/685；7.88%）通过手术获得，其余通过随访获得。总精度，灵敏度,PTCNB对恶性肿瘤诊断的特异性为94.45%,84.87%,100%,分别。PTCNB的诊断率为66.28%。与小于3厘米的病变相比，更高的诊断率（70.89%），病灶≥3cm组并发症发生率较低(38.22%),手术时间较短(8.78min)。
结论：PTCNB在持续巩固中是一种安全有效的手术，提供相对较高的诊断率和可接受的并发症，特别是大小超过3厘米的病变。
■CT引导同轴穿刺活检肺实变是一种安全有效的手术。同轴穿刺活检的诊断率高，并发症发生率低（包括气胸和肺内出血）。尤其是较大的病变。
