Abstract：
A wide spectrum of benign and malignant primary mesenchymal tumors and tumor-like lesions of the spleen has been recently included under the umbrella term \'stroma-derived\' neoplasms and tumor-like lesions. These include dendritic cell neoplasms such as follicular dendritic cell sarcoma, EBV-positive inflammatory follicular dendritic cell sarcoma, and fibroblastic reticular cell tumor; smooth muscle and myofibroblastic lesions such as inflammatory pseudotumor, EBV-associated smooth muscle tumor and undifferentiated pleomorphic sarcoma as well as a diverse spectrum of vascular and vascular-stromal tumors and tumor-like lesions. While some tumor and tumor-like lesions are unique to the spleen, others may also occur in diverse extra-splenic viscera. These tumors and tumor-like lesions demonstrate characteristic histopathology, immunocytochemistry and biological behavior. While cross-sectional imaging studies allow detection, staging and limited characterization of these splenic lesions, histopathological confirmation permits optimal management and surveillance strategies.
摘要：
最近，广泛的良性和恶性原发性间充质肿瘤和脾脏肿瘤样病变被纳入“基质衍生的肿瘤和肿瘤样病变”这一术语。这些包括树突细胞肿瘤，如滤泡树突细胞肉瘤，EBV阳性炎性滤泡树突状细胞肉瘤,和纤维母细胞网状细胞肿瘤;平滑肌和肌纤维母细胞病变，如炎性假瘤，EBV相关的平滑肌肿瘤和未分化的多形性肉瘤以及多种血管和血管间质肿瘤和肿瘤样病变。虽然有些肿瘤和肿瘤样病变是脾脏特有的，其他也可能发生在不同的脾外内脏。这些肿瘤和肿瘤样病变表现出特征性的组织病理学，免疫细胞化学和生物学行为。虽然横断面成像研究允许检测，这些脾病变的分期和有限的特征，组织病理学确认允许最佳管理和监测策略。
