Abstract：
OBJECTIVE: Various materials have been proposed for reconstructing orbital fractures. The materials used must meet certain criteria to ensure their suitability for restoring the structure and function of the organ. These criteria include biocompatibility, ease of application, non-toxicity, hypo-allergenicity, and non-carcinogenicity. In this study, we systematically reviewed the studies regarding the biomaterials in orbital implants and their clinical application.
METHODS: A comprehensive search across various databases, including PubMed, Scopus, EMBASE, Cochrane Library, and Web of Science, was conducted until April 10th, 2023. After retrieving the search results and eliminating duplicates, final studies were included after screening through defined criteria. Human and animal studies assessing the clinical application of biomaterials in orbital implants were included. The quality of the case series and controlled intervention studies were evaluated using the NIH tool, and for animal studies, the risk of bias was assessed using SYRCLE\'s tool.
RESULTS: Seventeen studies were included according to defined criteria. These studies aimed to explore the clinical application of biomaterials and examine the associated complications in orbital implants.
CONCLUSIONS: We found that using biomaterials did not result in elevated intraocular pressure (IOP). However, we did observe certain complications, with infection, residual diplopia, and enophthalmos being the most frequently reported issues.
METHODS: A comprehensive search across various databases, including PubMed, Scopus, EMBASE, Cochrane Library, and Web of Science, was conducted until April 10th, 2023. After retrieving the search results and eliminating duplicates, final studies were included after screening through defined criteria. Human and animal studies assessing the clinical application of biomaterials in orbital implants were included. The quality of the case series and controlled intervention studies were evaluated using the NIH tool, and for animal studies, the risk of bias was assessed using SYRCLE\'s tool.
RESULTS: Seventeen studies were included according to defined criteria. These studies aimed to explore the clinical application of biomaterials and examine the associated complications in orbital implants.
CONCLUSIONS: We found that using biomaterials did not result in elevated intraocular pressure (IOP). However, we did observe certain complications, with infection, residual diplopia, and enophthalmos being the most frequently reported issues.
摘要：
目的：已经提出了各种材料来重建眼眶骨折。所使用的材料必须符合一定的标准，以确保它们适合恢复器官的结构和功能。这些标准包括生物相容性，易于应用，无毒性，低致敏性,和非致癌性。在这项研究中,我们系统回顾了眼眶植入物中生物材料的研究及其临床应用。
方法：跨各种数据库的全面搜索，包括PubMed,Scopus,EMBASE,科克伦图书馆,和WebofScience,一直持续到4月10日，2023年。检索搜索结果并消除重复项之后，在通过定义的标准筛选后纳入最终研究.包括评估生物材料在眼眶植入物中的临床应用的人类和动物研究。使用NIH工具评估病例系列和对照干预研究的质量，对于动物研究，使用SYRCLE工具评估偏倚风险.
结果：根据定义的标准纳入了17项研究。这些研究旨在探索生物材料的临床应用，并检查眼眶植入物的相关并发症。
结论：我们发现使用生物材料不会导致眼内压（IOP）升高。然而,我们确实观察到了某些并发症，感染，残余复视,眼球内陷是最常见的问题。
方法：跨各种数据库的全面搜索，包括PubMed,Scopus,EMBASE,科克伦图书馆,和WebofScience,一直持续到4月10日，2023年。检索搜索结果并消除重复项之后，在通过定义的标准筛选后纳入最终研究.包括评估生物材料在眼眶植入物中的临床应用的人类和动物研究。使用NIH工具评估病例系列和对照干预研究的质量，对于动物研究，使用SYRCLE工具评估偏倚风险.
结果：根据定义的标准纳入了17项研究。这些研究旨在探索生物材料的临床应用，并检查眼眶植入物的相关并发症。
结论：我们发现使用生物材料不会导致眼内压（IOP）升高。然而,我们确实观察到了某些并发症，感染，残余复视,眼球内陷是最常见的问题。
