Abstract：
OBJECTIVE: This propensity score matching, multicenter, cross-sectional study was performed to examine the effects of various prosthetic methods for dental clinic outpatients with Kennedy Class I partial edentulism (KCIPE) on oral hypofunction, subjective frailty symptoms, and oral health-related quality of life (QOL).
METHODS: Patients (n = 348) were classified into the following three groups for analysis: NT, patients with natural dentition providing intermaxillary contact in four occlusal supporting zones; RPD, patients with KCIPE who received removable partial dentures; and ISFP, patients with KCIPE who received implant-supported fixed prostheses. Participants\' basic characteristics were recorded, and oral function tests were conducted. Subjective symptoms of physical and oral frailty were investigated via questionnaire. Oral health-related QOL was assessed using the Japanese short version of the Oral Health Impact Profile (OHIP-JP16). Propensity score matching was performed to adjust for patient background factors that could influence oral hypofunction in each group.
RESULTS: Compared with the ISFP group, the RPD group had significantly higher rates of poor oral hygiene, reduced occlusal force, decreased masticatory function, and declines in swallowing function and oral hypofunction; the odds ratio for oral hypofunction was 4.67. Compared with the ISFP group, the RPD group had significantly greater subjective symptoms of physical frailty and oral frailty, as well as higher OHIP scores.
CONCLUSIONS: Prosthetic treatment of KCIPE affected oral hypofunction, subjective frailty symptoms, and oral health-related QOL in dental clinic outpatients.
METHODS: Patients (n = 348) were classified into the following three groups for analysis: NT, patients with natural dentition providing intermaxillary contact in four occlusal supporting zones; RPD, patients with KCIPE who received removable partial dentures; and ISFP, patients with KCIPE who received implant-supported fixed prostheses. Participants\' basic characteristics were recorded, and oral function tests were conducted. Subjective symptoms of physical and oral frailty were investigated via questionnaire. Oral health-related QOL was assessed using the Japanese short version of the Oral Health Impact Profile (OHIP-JP16). Propensity score matching was performed to adjust for patient background factors that could influence oral hypofunction in each group.
RESULTS: Compared with the ISFP group, the RPD group had significantly higher rates of poor oral hygiene, reduced occlusal force, decreased masticatory function, and declines in swallowing function and oral hypofunction; the odds ratio for oral hypofunction was 4.67. Compared with the ISFP group, the RPD group had significantly greater subjective symptoms of physical frailty and oral frailty, as well as higher OHIP scores.
CONCLUSIONS: Prosthetic treatment of KCIPE affected oral hypofunction, subjective frailty symptoms, and oral health-related QOL in dental clinic outpatients.
摘要：
目标：此倾向评分匹配，多中心，进行了横断面研究，以检查各种修复方法对牙科诊所门诊患者的影响肯尼迪I类部分性脑萎缩症（KCIPE）对口腔功能减退，主观虚弱症状，与口腔健康相关的生活质量（QOL）。
方法：将患者（n=348）分为以下三组进行分析：NT，在四个咬合支撑区提供颌间接触的自然牙列患者；RPD，接受可移动局部义齿的KCIPE患者；和ISFP，接受植入物支持的固定假体的KCIPE患者。记录参与者的基本特征，并进行口腔功能测试。通过问卷调查调查身体和口腔虚弱的主观症状。使用日本简短版本的口腔健康影响概况（OHIP-JP16）评估口腔健康相关的QOL。进行倾向评分匹配以调整可能影响每组口腔功能减退的患者背景因素。
结果：与ISFP组相比，RPD组口腔卫生不良的发生率明显较高，降低了咬合力，咀嚼功能下降，吞咽功能和口腔功能减退下降；口腔功能减退的比值比为4.67。与ISFP组相比，RPD组有明显更大的身体虚弱和口腔虚弱的主观症状，以及更高的OHIP分数。
结论：KCIPE的修复治疗影响口腔功能减退，主观虚弱症状，口腔诊所门诊患者与口腔健康相关的生活质量。
方法：将患者（n=348）分为以下三组进行分析：NT，在四个咬合支撑区提供颌间接触的自然牙列患者；RPD，接受可移动局部义齿的KCIPE患者；和ISFP，接受植入物支持的固定假体的KCIPE患者。记录参与者的基本特征，并进行口腔功能测试。通过问卷调查调查身体和口腔虚弱的主观症状。使用日本简短版本的口腔健康影响概况（OHIP-JP16）评估口腔健康相关的QOL。进行倾向评分匹配以调整可能影响每组口腔功能减退的患者背景因素。
结果：与ISFP组相比，RPD组口腔卫生不良的发生率明显较高，降低了咬合力，咀嚼功能下降，吞咽功能和口腔功能减退下降；口腔功能减退的比值比为4.67。与ISFP组相比，RPD组有明显更大的身体虚弱和口腔虚弱的主观症状，以及更高的OHIP分数。
结论：KCIPE的修复治疗影响口腔功能减退，主观虚弱症状，口腔诊所门诊患者与口腔健康相关的生活质量。
