关键词: Histopathology Radiotherapy Sinonasal carcinomas Sinonasal malignancies Surgery Treatment

来  源:   DOI:10.1007/s11912-024-01566-x

Abstract:
OBJECTIVE: The purpose of this review is to analyze the diagnosis and treatments of the sinonasal malignant tumors throw systematic reviewed literature. The systematic review of the literature was performed according to PRISMA guidelines.
RESULTS: Total 11,653 cases of five article were analyzed. The cohort of 3824 cases received appropriate treatment. The most frequent histotype of the group of sinonasal malignancies was squamous cell carcinoma. Squamous cell carcinoma was represented by 54%. The other histopathological subtypes were esthesioneuroblastoma with 9,9%, melanoma 9,8%, adenocarcinoma 7,5%, sarcoma 7,3%, adeno cystic carcinoma 7,1%, sinonasal undifferentiated carcinoma 3,9%, sinonasal neuroendocrine carcinoma 2,8% respectively. All 772 cases of total 3824 were treated only surgically. All 62 cases of total 3824 were treated without surgery, 20 cases with proton technique and SFUD, and 42 cases with proton technique and IMRT. The other 2990 cases of total 3824 were treated with multimodality treatment. The diagnosis and treatment of sinonasal cancers require a interdisciplinary approach and multimodality treatment.
摘要:
目的:本综述的目的是对鼻窦恶性肿瘤的诊断和治疗进行系统的文献综述。根据PRISMA指南对文献进行系统综述。
结果:共分析5篇文献中的11,653例。3824例患者接受了适当的治疗。鼻窦恶性肿瘤组中最常见的组织型是鳞状细胞癌。鳞状细胞癌占54%。其他组织病理学亚型为美学神经母细胞瘤,占9.9%,黑色素瘤9.8%,腺癌7,5%,肉瘤7,3%,腺囊性癌7,1%,鼻窦未分化癌3,9%,鼻窦神经内分泌癌分别为2,8%。总共3824例中的772例仅通过手术治疗。3824例中62例,均未手术治疗。20例质子技术和SFUD,42例采用质子技术和IMRT。3824例中的其他2990例采用多模式治疗。鼻窦肿瘤的诊断和治疗需要跨学科的方法和多模式的治疗。
公众号