Abstract：
Purpose To investigate the ability of kilovolt-independent (hereafter, kV-independent) and tin filter spectral shaping to accurately quantify the coronary artery calcium score (CACS) and radiation dose reductions compared with the standard 120-kV CT protocol. Materials and Methods This prospective, blinded reader study included 201 participants (mean age, 60 years ± 9.8 [SD]; 119 female, 82 male) who underwent standard 120-kV CT and additional kV-independent and tin filter research CT scans from October 2020 to July 2021. Scans were reconstructed using a Qr36f kernel for standard scans and an Sa36f kernel for research scans simulating artificial 120-kV images. CACS, risk categorization, and radiation doses were compared by analyzing data with analysis of variance, Kruskal-Wallis test, Mann-Whitney test, Bland-Altman analysis, Pearson correlations, and κ analysis for agreement. Results There was no evidence of differences in CACS across standard 120-kV, kV-independent, and tin filter scans, with median CACS values of 1 (IQR, 0-48), 0.6 (IQR, 0-58), and 0 (IQR, 0-51), respectively (P = .85). Compared with standard 120-kV scans, kV-independent and tin filter scans showed excellent correlation in CACS values (r = 0.993 and r = 0.999, respectively), with high agreement in CACS risk categorization (κ = 0.95 and κ = 0.93, respectively). Standard 120-kV scans had a mean radiation dose of 2.09 mSv ± 0.84, while kV-independent and tin filter scans reduced it to 1.21 mSv ± 0.85 and 0.26 mSv ± 0.11, cutting doses by 42% and 87%, respectively (P < .001). Conclusion The kV-independent and tin filter research CT acquisition techniques showed excellent agreement and high accuracy in CACS estimation compared with standard 120-kV scans, with large reductions in radiation dose. Keywords: CT, Cardiac, Coronary Arteries, Radiation Safety, Coronary Artery Calcium Score, Radiation Dose Reduction, Low-Dose CT Scan, Tin Filter, kV-Independent Supplemental material is available for this article. © RSNA, 2024.
摘要：
目的研究千伏独立能力(以下，kV无关）和锡滤波器光谱整形，以与标准120kVCT协议相比，准确量化冠状动脉钙积分（CACS）和辐射剂量减少。材料和方法本前瞻性，盲人读者研究包括201名参与者(平均年龄，60岁±9.8[SD]；119名女性，82名男性），从2020年10月至2021年7月接受了标准120kVCT和额外的kV无关和锡过滤器研究CT扫描。使用用于标准扫描的Qr36f内核和用于模拟人工120kV图像的研究扫描的Sa36f内核重建扫描。CACS,风险分类，和辐射剂量通过方差分析分析进行比较，Kruskal-Wallis测试,曼-惠特尼测试,Bland-Altman分析,皮尔逊相关性，和κ分析的一致性。结果没有证据表明标准120kV之间的CACS存在差异，kV独立，和锡过滤器扫描，CACS中值为1(IQR，0-48），0.6(IQR，0-58），和0(IQR，0-51），分别（P=.85）。与标准的120kV扫描相比，kV无关扫描和锡滤波扫描在CACS值中显示出极好的相关性（分别为r=0.993和r=0.999），在CACS风险分类中具有很高的一致性(分别为κ=0.95和κ=0.93)。标准120kV扫描的平均辐射剂量为2.09mSv±0.84，而与kV无关的和锡过滤器扫描将其降低至1.21mSv±0.85和0.26mSv±0.11，削减剂量为42％和87％，分别(P<.001)。结论与标准120kV扫描相比，独立于kV和锡滤波器研究的CT采集技术在CACS估计中显示出极好的一致性和较高的准确性，辐射剂量大幅减少。关键词:CT,心脏,冠状动脉,辐射安全,冠状动脉钙积分,辐射剂量减少,低剂量CT扫描,锡过滤器，kV独立补充材料可用于本文。©RSNA,2024.
