Abstract：
UNASSIGNED: Sarcoidosis is a multi-system granulomatous disease of unknown origin. It is mainly thought of as a lung disease but it can affect any organ system. Sinus and endocrine dysfunctions are described but are rare and seldomly linked with sarcoidosis.
UNASSIGNED: Here we describe a case of a young Caucasian man who already visited multiple care givers for sinusitis, erectile dysfunction and anorexia. He presented at the emergency department with fever and emaciation, polyuria and polydipsia. The results of the blood sampling revealed a hypercalcaemia as well as abnormal thyroid function.
UNASSIGNED: After biochemical, radiological and histopathological workup, he was diagnosed with pulmonary sarcoidosis. Treatment with corticosteroids resulted in resolution of the sinusitis and normalisation of the calcemia, as well as the thyroid function while the impotence, polydipsia and polyuria remained. Elaboration revealed extra-pulmonary involvement of the sarcoidosis with dysfunction of the hypothalamic-pituitary axis with hypogonadotropic hypogonadism and diabetes insipidus due to a sellar mass.
UNASSIGNED: This is a rare case of systemic sarcoidosis with both thoracic and extra thoracic manifestations, with pituitary and sinus involvement. It shows that sarcoidosis can affect any organ system and diagnosis can be difficult in case of extrapulmonary manifestations.
UNASSIGNED: Here we describe a case of a young Caucasian man who already visited multiple care givers for sinusitis, erectile dysfunction and anorexia. He presented at the emergency department with fever and emaciation, polyuria and polydipsia. The results of the blood sampling revealed a hypercalcaemia as well as abnormal thyroid function.
UNASSIGNED: After biochemical, radiological and histopathological workup, he was diagnosed with pulmonary sarcoidosis. Treatment with corticosteroids resulted in resolution of the sinusitis and normalisation of the calcemia, as well as the thyroid function while the impotence, polydipsia and polyuria remained. Elaboration revealed extra-pulmonary involvement of the sarcoidosis with dysfunction of the hypothalamic-pituitary axis with hypogonadotropic hypogonadism and diabetes insipidus due to a sellar mass.
UNASSIGNED: This is a rare case of systemic sarcoidosis with both thoracic and extra thoracic manifestations, with pituitary and sinus involvement. It shows that sarcoidosis can affect any organ system and diagnosis can be difficult in case of extrapulmonary manifestations.
摘要：
■结节病是一种不明原因的多系统肉芽肿性疾病。它主要被认为是一种肺部疾病，但它可以影响任何器官系统。描述了窦和内分泌功能障碍，但很少见，并且与结节病有关。
在这里，我们描述了一个年轻的白人男子，他已经拜访了多个鼻窦炎患者，勃起功能障碍和厌食症。他在急诊科出现发烧和消瘦，多尿和多饮。血液采样结果显示高钙血症以及甲状腺功能异常。
■生化后，放射学和组织病理学检查，他被诊断为肺结节病。用皮质类固醇治疗导致鼻窦炎的消退和钙血症的正常化。以及阳痿时的甲状腺功能，仍然存在多饮和多尿。详细说明显示结节病的肺外受累，下丘脑-垂体轴功能障碍，低促性腺激素性性腺功能减退和由于鞍区肿块引起的尿崩症。
■这是一例罕见的系统性结节病，有胸部和胸部外表现，垂体和鼻窦受累。它表明结节病可以影响任何器官系统，并且在肺外表现的情况下诊断可能很困难。
在这里，我们描述了一个年轻的白人男子，他已经拜访了多个鼻窦炎患者，勃起功能障碍和厌食症。他在急诊科出现发烧和消瘦，多尿和多饮。血液采样结果显示高钙血症以及甲状腺功能异常。
■生化后，放射学和组织病理学检查，他被诊断为肺结节病。用皮质类固醇治疗导致鼻窦炎的消退和钙血症的正常化。以及阳痿时的甲状腺功能，仍然存在多饮和多尿。详细说明显示结节病的肺外受累，下丘脑-垂体轴功能障碍，低促性腺激素性性腺功能减退和由于鞍区肿块引起的尿崩症。
■这是一例罕见的系统性结节病，有胸部和胸部外表现，垂体和鼻窦受累。它表明结节病可以影响任何器官系统，并且在肺外表现的情况下诊断可能很困难。
