Abstract：
This study aims to explore the essential functional requirements associated with controlling the proliferation of microbes in the domain of textiles used in public health areas. Herein, three antimicrobial agents, specifically iodopropylbutylcarbamate (IPBC), 1-hydroxypyridine-2-thioketone zinc (ZPT), and 2-octyl-3-isothiazolinone (OIT), were chosen for fabric finishing based on their notable effectiveness, minimal toxicity, cost-efficiency, and chemical stability. Utilizing Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) as representative bacterial strains, the Minimum Inhibitory Concentration (MIC50) of individual and combined antimicrobial agents was measured, and their antimicrobial effectiveness was rigorously evaluated. Concurrently, the antimicrobial effectiveness, whiteness, and mechanical durability of the fabric following antimicrobial treatment were thoroughly examined. The results demonstrate that some combinations of the three antimicrobial agents elicit additive effects on both S. aureus and E. coli. Notably, at an equivalent ratio of IPBC, ZPT, and OIT and a total concentration of 0.2 wt. %, the inhibition rates against both bacterial strains surpass 99%. Upon application to nylon fabric, the treated material demonstrates significant antimicrobial properties, with minimal reduction observed in the whiteness and tensile strength of the treated nylon. This study provides practicable strategies relevant to the production of textiles endowed with antimicrobial properties.
摘要：
本研究旨在探索与控制公共卫生领域纺织品中微生物增殖相关的基本功能要求。在这里，三种抗菌剂，特别是氨基甲酸碘丙基丁酯（IPBC），1-羟基吡啶-2-硫酮锌（ZPT），和2-辛基-3-异噻唑啉酮（OIT），根据其显著的效果选择织物整理，最小的毒性，成本效益，和化学稳定性。利用金黄色葡萄球菌(S.金黄色葡萄球菌)和大肠杆菌(E.大肠杆菌)作为代表性细菌菌株，测量了单个和组合抗菌剂的最小抑制浓度（MIC50），并且对其抗菌效果进行了严格评估.同时,抗菌效果，白度,彻底检查抗菌处理后织物的机械耐久性。结果表明,三种抗微生物剂的一些组合引起对金黄色葡萄球菌和大肠杆菌两者的累加效应。值得注意的是,以IPBC的当量比，ZPT,和OIT,总浓度为0.2wt.%,对两种细菌菌株的抑制率均超过99％。应用于尼龙织物时，处理过的材料表现出显著的抗菌性能，在处理过的尼龙的白度和拉伸强度中观察到最小的降低。这项研究提供了与具有抗菌性能的纺织品生产相关的可行策略。
