Abstract：
BACKGROUND: The early and rapid identification of psychosomatic symptoms is crucial to prevent harmful outcomes in patients with human papillomavirus (HPV) infection in busy comprehensive clinics. This study aimed to explore the prevalence and rapid screening method of the Diagnostic Criteria for Psychosomatic Research-revised (DCPR) syndromes in patients with HPV infection.
METHODS: A total of 504 participants underwent a clinical assessment that included DCPR, Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5), the Social Support Rating Scale (SSRS), the Simplified Coping Style Questionnaire (SCSQ), fear of disease, sociodemographic and clinical characteristics. The prevalence of DCPR syndromes and DSM-5 diagnoses were compared between the HPV-positive and negative patients using χ2 tests. We explored the rapid screen indicator through multiple logistic regression analyses of the participants\' psychosocial factors, sociodemographic and clinical characteristics.
RESULTS: The incidence of DCPR syndromes in HPV-positive patients (56.6%) was significantly greater than that in HPV-negative patients (17.3%) and DSM-5 diagnoses (8.5%) in the HPV-positive group. Health anxiety, irritable mood, type A behavior, and demoralization were the most common psychosomatic syndromes in HPV-positive patients. As the degree of fear increased from 0 to 5 to 10, the risk of DCPR increased from 1.27 (95% CI: 0.21-7.63) to 3.24 (score range: 1-5, 95% CI: 1.01-10.39) to 9.91 (score range: 6-10, 95% CI: 3.21-30.62) in the HPV-positive group.
CONCLUSIONS: The degree of fear, as an independent risk factor, could be used to quickly screen outpatients with a high risk of DCPR syndrome among women with HPV infection.
METHODS: A total of 504 participants underwent a clinical assessment that included DCPR, Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5), the Social Support Rating Scale (SSRS), the Simplified Coping Style Questionnaire (SCSQ), fear of disease, sociodemographic and clinical characteristics. The prevalence of DCPR syndromes and DSM-5 diagnoses were compared between the HPV-positive and negative patients using χ2 tests. We explored the rapid screen indicator through multiple logistic regression analyses of the participants\' psychosocial factors, sociodemographic and clinical characteristics.
RESULTS: The incidence of DCPR syndromes in HPV-positive patients (56.6%) was significantly greater than that in HPV-negative patients (17.3%) and DSM-5 diagnoses (8.5%) in the HPV-positive group. Health anxiety, irritable mood, type A behavior, and demoralization were the most common psychosomatic syndromes in HPV-positive patients. As the degree of fear increased from 0 to 5 to 10, the risk of DCPR increased from 1.27 (95% CI: 0.21-7.63) to 3.24 (score range: 1-5, 95% CI: 1.01-10.39) to 9.91 (score range: 6-10, 95% CI: 3.21-30.62) in the HPV-positive group.
CONCLUSIONS: The degree of fear, as an independent risk factor, could be used to quickly screen outpatients with a high risk of DCPR syndrome among women with HPV infection.
摘要：
背景：在繁忙的综合诊所中，早期快速识别心身症状对于预防人乳头瘤病毒（HPV）感染患者的有害结局至关重要。本研究旨在探讨HPV感染患者心身研究修订（DCPR）综合征诊断标准的患病率和快速筛查方法。
方法：共有504名参与者接受了包括DCPR在内的临床评估，精神疾病诊断和统计手册，第五版（DSM-5），社会支持评定量表(SSRS)，简化的应对方式问卷(SCSQ)，对疾病的恐惧,社会人口统计学和临床特征。使用χ2检验比较HPV阳性和阴性患者的DCPR综合征和DSM-5诊断的患病率。我们通过对参与者的心理社会因素进行多元逻辑回归分析，探索了快速筛查指标，社会人口统计学和临床特征。
结果：HPV阳性患者的DCPR综合征发生率（56.6%）明显高于HPV阴性患者（17.3%）和DSM-5诊断患者（8.5%）。健康焦虑，烦躁的情绪，类型A行为，和士气低落是HPV阳性患者中最常见的心身综合征.随着恐惧程度从0增加到5增加到10，HPV阳性组DCPR的风险从1.27（95％CI：0.21-7.63）增加到3.24（评分范围：1-5，95％CI：1.01-10.39）到9.91（评分范围：6-10，95％CI：3.21-30.62）。
结论：恐惧的程度，作为一个独立的风险因素，可用于快速筛查HPV感染女性中DCPR综合征高风险门诊患者。
方法：共有504名参与者接受了包括DCPR在内的临床评估，精神疾病诊断和统计手册，第五版（DSM-5），社会支持评定量表(SSRS)，简化的应对方式问卷(SCSQ)，对疾病的恐惧,社会人口统计学和临床特征。使用χ2检验比较HPV阳性和阴性患者的DCPR综合征和DSM-5诊断的患病率。我们通过对参与者的心理社会因素进行多元逻辑回归分析，探索了快速筛查指标，社会人口统计学和临床特征。
结果：HPV阳性患者的DCPR综合征发生率（56.6%）明显高于HPV阴性患者（17.3%）和DSM-5诊断患者（8.5%）。健康焦虑，烦躁的情绪，类型A行为，和士气低落是HPV阳性患者中最常见的心身综合征.随着恐惧程度从0增加到5增加到10，HPV阳性组DCPR的风险从1.27（95％CI：0.21-7.63）增加到3.24（评分范围：1-5，95％CI：1.01-10.39）到9.91（评分范围：6-10，95％CI：3.21-30.62）。
结论：恐惧的程度，作为一个独立的风险因素，可用于快速筛查HPV感染女性中DCPR综合征高风险门诊患者。
