PDF(Pubmed)
Abstract：
UNASSIGNED: This study aimed to investigate coronavirus disease 2019 (COVID-19) vaccination rates and factors affecting vaccination in children with rheumatic diseases.
UNASSIGNED: This multicenter cross-sectional survey-based study was conducted between July 2022 and September 2022. Four hundred seventy-four patients (256 females, 218 males; median age: 15 years; interquartile range, 13 to 16 years) were included in the patient group, and 211 healthy children (124 females, 87 males; median age: 15 years; interquartile range, 13 to 16 years) were included in the control group. A questionnaire was administered to the parents face-to-face during routine outpatient visits.
UNASSIGNED: Of the patients, 220 were followed up with the diagnosis of autoinflammatory disease, 174 with juvenile idiopathic arthritis, 48 with connective tissue disease, 23 with vasculitis, eight with uveitis, and one with sarcoidosis. In the study group, 256 (54%) patients and 115 (54.5%) healthy children received at least one dose of COVID-19 vaccine. Parents\' concern regarding potential side effects of the vaccine was the most common reason for COVID-19 vaccination hesitancy in both groups. The median patient age, follow-up period, colchicine treatment rates, childhood vaccination and influenza vaccination rates, median parental age, parental vaccination rate, and parental education level were higher in vaccinated patients (p<0.001).
UNASSIGNED: Parents\' concerns about safety and side effects were found to be the most important factors affecting vaccination success. Identification of the underlying causes of parental vaccine hesitancy will facilitate the development of effective vaccination strategies for potential future outbreaks.
UNASSIGNED: This multicenter cross-sectional survey-based study was conducted between July 2022 and September 2022. Four hundred seventy-four patients (256 females, 218 males; median age: 15 years; interquartile range, 13 to 16 years) were included in the patient group, and 211 healthy children (124 females, 87 males; median age: 15 years; interquartile range, 13 to 16 years) were included in the control group. A questionnaire was administered to the parents face-to-face during routine outpatient visits.
UNASSIGNED: Of the patients, 220 were followed up with the diagnosis of autoinflammatory disease, 174 with juvenile idiopathic arthritis, 48 with connective tissue disease, 23 with vasculitis, eight with uveitis, and one with sarcoidosis. In the study group, 256 (54%) patients and 115 (54.5%) healthy children received at least one dose of COVID-19 vaccine. Parents\' concern regarding potential side effects of the vaccine was the most common reason for COVID-19 vaccination hesitancy in both groups. The median patient age, follow-up period, colchicine treatment rates, childhood vaccination and influenza vaccination rates, median parental age, parental vaccination rate, and parental education level were higher in vaccinated patients (p<0.001).
UNASSIGNED: Parents\' concerns about safety and side effects were found to be the most important factors affecting vaccination success. Identification of the underlying causes of parental vaccine hesitancy will facilitate the development of effective vaccination strategies for potential future outbreaks.
摘要：
■本研究旨在调查2019年冠状病毒病（COVID-19）疫苗接种率和影响风湿性疾病儿童疫苗接种的因素。
■这项基于多中心横断面调查的研究是在2022年7月至2022年9月之间进行的。494名患者(256名女性，218名男性；平均年龄：15岁；四分位距，13至16岁）纳入患者组，和211名健康儿童(124名女性，87名男性；平均年龄：15岁；四分位数间距，13至16岁）纳入对照组。在例行门诊就诊期间，对父母进行了面对面的问卷调查。
■患者，220例随访诊断为自身炎症性疾病，174患有青少年特发性关节炎，48患有结缔组织病，23患有血管炎，八个患有葡萄膜炎，还有一个是结节病.在研究小组中,256名（54%）患者和115名（54.5%）健康儿童接受了至少一剂COVID-19疫苗。父母对疫苗潜在副作用的担忧是两组COVID-19疫苗接种犹豫不决的最常见原因。患者年龄中位数，随访期,秋水仙碱治疗率，儿童疫苗接种和流感疫苗接种率，父母年龄中位数，父母的疫苗接种率，接种疫苗患者的父母教育水平较高（p<0.001）。
父母对安全性和副作用的担忧被认为是影响疫苗接种成功的最重要因素。确定父母疫苗犹豫的根本原因将有助于为潜在的未来爆发制定有效的疫苗接种策略。
■这项基于多中心横断面调查的研究是在2022年7月至2022年9月之间进行的。494名患者(256名女性，218名男性；平均年龄：15岁；四分位距，13至16岁）纳入患者组，和211名健康儿童(124名女性，87名男性；平均年龄：15岁；四分位数间距，13至16岁）纳入对照组。在例行门诊就诊期间，对父母进行了面对面的问卷调查。
■患者，220例随访诊断为自身炎症性疾病，174患有青少年特发性关节炎，48患有结缔组织病，23患有血管炎，八个患有葡萄膜炎，还有一个是结节病.在研究小组中,256名（54%）患者和115名（54.5%）健康儿童接受了至少一剂COVID-19疫苗。父母对疫苗潜在副作用的担忧是两组COVID-19疫苗接种犹豫不决的最常见原因。患者年龄中位数，随访期,秋水仙碱治疗率，儿童疫苗接种和流感疫苗接种率，父母年龄中位数，父母的疫苗接种率，接种疫苗患者的父母教育水平较高（p<0.001）。
父母对安全性和副作用的担忧被认为是影响疫苗接种成功的最重要因素。确定父母疫苗犹豫的根本原因将有助于为潜在的未来爆发制定有效的疫苗接种策略。
