A Case of Infective Endocarditis in a Middle-Aged Patient With Trisomy 21 and an Incidentally Discovered Patent Foramen Ovale (PFO).

患有 21 三体和偶然发现卵圆孔未闭 （ PFO ） 的中年患者的感染性心内膜炎病例。

• 发表时间: 2024 May
• 来源期刊: Cureus
• DOI: 10.7759/cureus.61106
• PMID: 38933636
• 文章类型: Case Reports
• 作者列表: Bhagwandeen SN,Ayele GM,Boampong AD,Bhagwandeen VJ,Grewal N,Williams CC,Skific R,Arhinful B,Sandhu H

关键词: congenital heart disease; down's syndrome; infective endocarditis; patent foramen ovale; trisomy 21

Abstract

Trisomy 21 often leads to cardiac complications, usually associated with congenital heart disease, such as atrial septal defects, ventricular septal defects, and patent ductus arteriosus. This case describes an unexpected instance of infective endocarditis (IE) in a middle-aged patient with an incidentally discovered patent foramen ovale (PFO). The common risk factors for IE include previous valve surgery, artificial heart valves, pacemakers, prior IE, congenital defects like bicuspid aortic valve, IV drug use, and the congenital defects mentioned earlier.

摘要

21三体常导致心脏并发症,通常与先天性心脏病有关，比如房间隔缺损,室间隔缺损,动脉导管未闭.该病例描述了一名意外发现的卵圆孔未闭（PFO）的中年患者的感染性心内膜炎（IE）。IE的常见风险因素包括以前的瓣膜手术，人工心脏瓣膜,起搏器,先前的IE，先天性缺陷，如二叶主动脉瓣，IV吸毒，和前面提到的先天性缺陷。