PDF(Pubmed)
Abstract：
BACKGROUND: Dental implantology is continually evolving in its quest to discover new biomaterials to improve dental implant success rates. The study explored the potential of innovative biomaterials for dental implant surfaces, including titanium-zirconium (Ti-Zr) alloy, hydroxyapatite-coated titanium (HA-Ti), and porous polyetheretherketone (PEEK), in comparison to conventional commercially pure titanium (CP Ti).
METHODS: A total of 186 samples were harvested for the analysis. Biomaterials were thoroughly evaluated in terms of surface topography, chemical composition, biocompatibility, mechanical properties, osseointegration performance, and bacterial adhesion. Study methods and techniques included scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), cell culture variants, tensile tests, hardness measurements, histological analysis, and microbiological testing.
RESULTS: Surface topography examination showed significant disparities between the biomaterials: Ti-Zr had a better roughness of 1.23 μm, while HA-Ti demonstrated a smoother surface at 0.98 μm. Chemical composition evaluation indicated the presence of a Ti-Zr alloy in Ti-Zr, calcium-phosphorus richness in HA-Ti, and high titanium amounts in CP Ti. The mechanical properties assessment showed that Ti-Zr and CP Ti had good tensile strengths of 750 MPa and 320 HV. In addition, bacterial adhesion tests showed low propensities for Ti-Zr and HA-Ti at 1200 and 800 cfu/cm2, respectively.
CONCLUSIONS: Ti-Zr and HA-Ti performed better than the other biomaterials in surface topography and mechanical properties and against bacterial adhesion. This study emphasizes that multi-parameter analysis is critical for clinical decision-making, allowing for the selection of the currently available biomaterial, which could be conducive to the long-term success of the implant.
METHODS: A total of 186 samples were harvested for the analysis. Biomaterials were thoroughly evaluated in terms of surface topography, chemical composition, biocompatibility, mechanical properties, osseointegration performance, and bacterial adhesion. Study methods and techniques included scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), cell culture variants, tensile tests, hardness measurements, histological analysis, and microbiological testing.
RESULTS: Surface topography examination showed significant disparities between the biomaterials: Ti-Zr had a better roughness of 1.23 μm, while HA-Ti demonstrated a smoother surface at 0.98 μm. Chemical composition evaluation indicated the presence of a Ti-Zr alloy in Ti-Zr, calcium-phosphorus richness in HA-Ti, and high titanium amounts in CP Ti. The mechanical properties assessment showed that Ti-Zr and CP Ti had good tensile strengths of 750 MPa and 320 HV. In addition, bacterial adhesion tests showed low propensities for Ti-Zr and HA-Ti at 1200 and 800 cfu/cm2, respectively.
CONCLUSIONS: Ti-Zr and HA-Ti performed better than the other biomaterials in surface topography and mechanical properties and against bacterial adhesion. This study emphasizes that multi-parameter analysis is critical for clinical decision-making, allowing for the selection of the currently available biomaterial, which could be conducive to the long-term success of the implant.
摘要：
背景：牙种植学在不断发展中寻求发现新的生物材料以提高牙种植成功率。该研究探索了用于牙种植体表面的创新生物材料的潜力，包括钛锆（Ti-Zr）合金，羟基磷灰石涂层钛(HA-Ti),和多孔聚醚醚酮(PEEK)，与常规商业纯钛(CPTi)相比。
方法:共收集186个样品用于分析。生物材料在表面形貌方面进行了彻底评估，化学成分,生物相容性，机械性能，骨整合性能，和细菌粘附。研究方法和技术包括扫描电子显微镜(SEM)、能量色散X射线光谱（EDS），细胞培养变体，拉伸试验,硬度测量，组织学分析,和微生物测试。
结果：表面形貌检查显示生物材料之间存在显着差异：Ti-Zr具有1.23μm的更好粗糙度，而HA-Ti在0.98μm处表现出更光滑的表面。化学成分评估表明在Ti-Zr中存在Ti-Zr合金，HA-Ti中的钙磷丰富度，CPTi中的钛含量很高。力学性能评估表明，Ti-Zr和CPTi具有良好的拉伸强度，分别为750MPa和320HV。此外,细菌粘附试验显示，Ti-Zr和HA-Ti分别在1200和800cfu/cm2时低。
结论：Ti-Zr和HA-Ti在表面形貌和机械性能以及抗细菌粘附方面优于其他生物材料。这项研究强调，多参数分析对临床决策至关重要，允许选择当前可用的生物材料，这可能有助于植入物的长期成功。
方法:共收集186个样品用于分析。生物材料在表面形貌方面进行了彻底评估，化学成分,生物相容性，机械性能，骨整合性能，和细菌粘附。研究方法和技术包括扫描电子显微镜(SEM)、能量色散X射线光谱（EDS），细胞培养变体，拉伸试验,硬度测量，组织学分析,和微生物测试。
结果：表面形貌检查显示生物材料之间存在显着差异：Ti-Zr具有1.23μm的更好粗糙度，而HA-Ti在0.98μm处表现出更光滑的表面。化学成分评估表明在Ti-Zr中存在Ti-Zr合金，HA-Ti中的钙磷丰富度，CPTi中的钛含量很高。力学性能评估表明，Ti-Zr和CPTi具有良好的拉伸强度，分别为750MPa和320HV。此外,细菌粘附试验显示，Ti-Zr和HA-Ti分别在1200和800cfu/cm2时低。
结论：Ti-Zr和HA-Ti在表面形貌和机械性能以及抗细菌粘附方面优于其他生物材料。这项研究强调，多参数分析对临床决策至关重要，允许选择当前可用的生物材料，这可能有助于植入物的长期成功。
