关键词: Diagnosis Related Groups Total parenteral nutrition haematopoietic cell transplantation pharmacists

来  源:   DOI:10.1080/20523211.2024.2361320   PDF(Pubmed)

Abstract:
UNASSIGNED: Within Diagnosis Related Groups, based on service capability, efficiency, and quality safety assessment, clinical pharmacists contribute to promoting rational drug utilisation in healthcare institutions. However, a deficiency of pharmacist involvement has been observed in the total parenteral nutrition support to patients following haematopoietic cell transplantation (HCT) within DRGs.
UNASSIGNED: This study involved 146 patients who underwent HCT at the Department of Haematology, the Second Affiliated Hospital of Dalian Medical University, spanning from January 2020 to December 2022.
UNASSIGNED: Patients were allocated equally, with 73 in the control group and 73 in the pharmacist-involved group: baseline characteristics showed no statistics significance, including age, body mass index, nutrition risk screening-2002 score, liver and kidney function, etc. Albumin levels, prealbumin levels were significantly improved after a 7-day TPN support (34.92 ± 4.24 vs 36.25 ± 3.65, P = 0.044; 251.30 ± 95.72 vs 284.73 ± 83.15, P = 0.026). The body weight was increased after a 7-day support and before discharge (58.77 ± 12.47 vs 63.82 ± 11.70, P = 0.013; 57.61 ± 11.85 vs 64.92 ± 11.71, P < 0.001). The length of hospital stay, costs and the rate of re-admissions were significantly shortened (51.10 ± 1.42 vs 46.41 ± 1.86, P = 0.048; 360,162.67 ± 91,831.34 vs 324,070.16 ± 112,315.51, P = 0.035; 61.64% vs 43.84%, P = 0.046).
UNASSIGNED: Pharmacist-joint TPN support enhances the service efficiency score of medical units, ensuring the fulfilment of orders and rational medication.
摘要:
在诊断相关组中,基于服务能力,效率,和质量安全评估,临床药师有助于促进医疗机构合理使用药物。然而,在DRG内造血细胞移植(HCT)后的患者的全胃肠外营养支持中,观察到药剂师参与不足。
这项研究涉及146名在血液科接受HCT的患者,大连医科大学附属第二医院,从2020年1月到2022年12月。
患者平均分配,对照组73例,药剂师参与组73例:基线特征无统计学意义,包括年龄,身体质量指数,营养风险筛查-2002评分,肝肾功能,等。白蛋白水平,前白蛋白水平在7天TPN支持后显著改善(34.92±4.24vs36.25±3.65,P=0.044;251.30±95.72vs284.73±83.15,P=0.026).7天后和出院前体重增加(58.77±12.47vs63.82±11.70,P=0.013;57.61±11.85vs64.92±11.71,P<0.001)。住院时间长短,费用和再入院率显著缩短(51.10±1.42vs46.41±1.86,P=0.048;360,162.67±91,831.34vs324,070.16±112,315.51,P=0.035;61.64%vs43.84%,P=0.046)。
药剂师联合TPN支持提高了医疗单位的服务效率评分,确保订单的履行和合理用药。
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