PDF(Pubmed)
Abstract：
UNASSIGNED: Psychological factors and patients\' health-related quality of life (HRQOL) affect the outcome of patients with type 1 diabetes mellitus (T1DM). In this study, we aimed to determine the HRQOL status in patients with T1DM and its association with glycemic control and medication adherence.
UNASSIGNED: In this cross-sectional study, 227 T1DM patients were selected from the diabetes clinic, Imam Ali Hospital, Alborz University of Medical Sciences, and the Gabric database registry from 2020 to 2022. Demographic and diabetes characteristic checklist, medication adherence questionnaire (8-item Morisky Medication Adherence Scale (MMAS)), and QOL questionnaires (Short-Form-12 and PedsQL) were filled. Independent sample T-test was used to assess mean of QOL subscales with glycemic control and medication adherence. A logistic regression model was used to evaluate the association between glycemic control and medication adherence with QOl.
UNASSIGNED: Overall QOL scores in adults and children were 33.4 ± 7.1 based on Short-Form-12 and 76.2 ± 17.8 based on PedsQL, respectively. It was demonstrated that adults with Moderate/High adherence had higher QOL (p-value = 0.007). Likewise, Children with good glycemic control had higher psychosocial health scores (0.048). Logistic regression analysis did not reveal a significant association between adherence and QOL or Glycemic control and QOL in both adjusted and crude models.
UNASSIGNED: Better glycemic control and medication adherence in children and adults, respectively, are related to the psychological aspects of QOL. We suggest that emotional intelligence, which is replaced by other predictors during adulthood, may contribute to glycemic control in children in the early years following diagnosis.
UNASSIGNED: In this cross-sectional study, 227 T1DM patients were selected from the diabetes clinic, Imam Ali Hospital, Alborz University of Medical Sciences, and the Gabric database registry from 2020 to 2022. Demographic and diabetes characteristic checklist, medication adherence questionnaire (8-item Morisky Medication Adherence Scale (MMAS)), and QOL questionnaires (Short-Form-12 and PedsQL) were filled. Independent sample T-test was used to assess mean of QOL subscales with glycemic control and medication adherence. A logistic regression model was used to evaluate the association between glycemic control and medication adherence with QOl.
UNASSIGNED: Overall QOL scores in adults and children were 33.4 ± 7.1 based on Short-Form-12 and 76.2 ± 17.8 based on PedsQL, respectively. It was demonstrated that adults with Moderate/High adherence had higher QOL (p-value = 0.007). Likewise, Children with good glycemic control had higher psychosocial health scores (0.048). Logistic regression analysis did not reveal a significant association between adherence and QOL or Glycemic control and QOL in both adjusted and crude models.
UNASSIGNED: Better glycemic control and medication adherence in children and adults, respectively, are related to the psychological aspects of QOL. We suggest that emotional intelligence, which is replaced by other predictors during adulthood, may contribute to glycemic control in children in the early years following diagnosis.
摘要：
■心理因素和患者健康相关生活质量（HRQOL）影响1型糖尿病（T1DM）患者的预后。在这项研究中,我们旨在确定T1DM患者的HRQOL状态及其与血糖控制和药物依从性的关系.
■在这项横断面研究中，从糖尿病门诊选择227例T1DM患者，伊玛目阿里医院,Alborz医学科学大学,以及2020年至2022年的Gabric数据库注册表。人口统计和糖尿病特征检查表，药物依从性问卷（8项Morisky药物依从性量表（MMAS）），并填写了QOL问卷(Short-Form-12和PedsQL)。使用独立样本T检验评估具有血糖控制和药物依从性的QOL分量表的平均值。使用逻辑回归模型来评估血糖控制与药物依从性与QOl之间的关联。
■基于Short-Form-12的成人和儿童的总体生活质量分数为33.4±7.1，基于PedsQL的总体生活质量分数为76.2±17.8，分别。研究表明，中等/高依从性的成年人有较高的生活质量（p值=0.007）。同样，血糖控制良好的儿童有更高的社会心理健康评分（0.048）。Logistic回归分析显示，在调整模型和粗模型中，依从性与QOL或血糖控制与QOL之间均无显著关联。
■儿童和成人的血糖控制和用药依从性更好，分别,与QOL的心理方面有关。我们认为情绪智力，在成年期间被其他预测因子取代，可能有助于儿童在诊断后的早期血糖控制。
■在这项横断面研究中，从糖尿病门诊选择227例T1DM患者，伊玛目阿里医院,Alborz医学科学大学,以及2020年至2022年的Gabric数据库注册表。人口统计和糖尿病特征检查表，药物依从性问卷（8项Morisky药物依从性量表（MMAS）），并填写了QOL问卷(Short-Form-12和PedsQL)。使用独立样本T检验评估具有血糖控制和药物依从性的QOL分量表的平均值。使用逻辑回归模型来评估血糖控制与药物依从性与QOl之间的关联。
■基于Short-Form-12的成人和儿童的总体生活质量分数为33.4±7.1，基于PedsQL的总体生活质量分数为76.2±17.8，分别。研究表明，中等/高依从性的成年人有较高的生活质量（p值=0.007）。同样，血糖控制良好的儿童有更高的社会心理健康评分（0.048）。Logistic回归分析显示，在调整模型和粗模型中，依从性与QOL或血糖控制与QOL之间均无显著关联。
■儿童和成人的血糖控制和用药依从性更好，分别,与QOL的心理方面有关。我们认为情绪智力，在成年期间被其他预测因子取代，可能有助于儿童在诊断后的早期血糖控制。
