ONECUT2 在腺癌以及前列腺癌的神经内分泌变异中充当谱系可塑性驱动因子。
Mesh : Male Humans Receptors, Androgen / metabolism genetics Adenocarcinoma / genetics pathology metabolism drug therapy Receptors, Glucocorticoid / metabolism genetics Prostatic Neoplasms / genetics pathology metabolism drug therapy Drug Resistance, Neoplasm / genetics Benzamides / pharmacology Cell Line, Tumor Nitriles / pharmacology Gene Expression Regulation, Neoplastic Phenylthiohydantoin / pharmacology analogs & derivatives Nerve Tissue Proteins / genetics metabolism Epigenesis, Genetic RNA-Binding Proteins / metabolism genetics Neuroendocrine Tumors / genetics pathology metabolism drug therapy Animals Cell Lineage / genetics Mice
来 源:
DOI:10.1093/nar/gkae547
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