METHODS: The questionnaire was used in 366 patients with chronic pruritus of different etiologies from Germany (University Hospitals Heidelberg, Münster, Mainz, Erlangen, Giessen, private practice Bad Bentheim, TU Munich, Wiesbaden Kidney Center), Austria (Graz University Hospital) and Switzerland (Aarau Cantonal Hospital).
RESULTS: The reliability for repeated completion (retest reliability) with regard to localization, first occurrence, and concomitant diseases showed high values for Cohen\'s kappa (> 0.8). The data on the retest reliability of the pruritus characteristics showed lower values (< 0.7). With regard to the measurability of practically relevant changes (change sensitivity), medium to strong effect sizes were found (0.09-0.19). A statistically significant differentiation of the pruritus etiologies based on the recorded parameters was not possible.
CONCLUSIONS: The German Pruritus Questionnaire allows a comprehensive and structured recording of patient- and clinician-reported, relevant dimensions of chronic pruritus of different etiologies. Further adaptation and development are planned.
方法:问卷用于366名来自德国的不同病因的慢性瘙痒患者(海德堡大学医院,明斯特,美因茨,Erlangen,吉森,私人实践BadBentheim,慕尼黑工业大学,威斯巴登肾脏中心),奥地利(格拉茨大学医院)和瑞士(阿劳州医院)。
结果:关于本地化的重复完成的可靠性(重新测试可靠性),第一次出现,和伴随疾病的Cohen\skappa值很高(>0.8)。瘙痒特征的重测可靠性数据显示较低的值(<0.7)。关于实际相关变化的可测量性(变化灵敏度),发现中等到强效应大小(0.09-0.19)。不可能根据记录的参数对瘙痒病因进行统计学上的显着区分。
结论:德国瘙痒问卷允许对患者和临床医生报告的全面和结构化记录,不同病因慢性瘙痒的相关维度。计划进一步适应和发展。