Spiro - 氮杂环丁烷 Oxindoles 作为暴露前预防呼吸道合胞病毒感染的长效注射剂。
Mesh : Humans Respiratory Syncytial Virus Infections / prevention & control drug therapy Animals Oxindoles / chemistry pharmacology Spiro Compounds / chemistry pharmacology pharmacokinetics administration & dosage Antiviral Agents / pharmacology chemistry administration & dosage Azetidines / chemistry pharmacology administration & dosage pharmacokinetics Pre-Exposure Prophylaxis / methods Injections, Intramuscular Indoles / chemistry administration & dosage pharmacology Injections, Subcutaneous Respiratory Syncytial Virus, Human / drug effects Virus Internalization / drug effects
来 源: DOI:10.1021/acs.jmedchem.4c00514