PDF(Pubmed)
Abstract：
No vaccine has been more effective in reducing disease burden, especially in preventing child deaths, than measles-containing vaccine. The return on investment makes measles-containing vaccine one of the most cost-effective public health measures available. Exhaustive reviews of biological, technical, economic and programmatic evidence have concluded that measles can and should be eradicated, and by including rubella antigen in measles-containing vaccine, congenital rubella syndrome will also be eradicated. All World Health Organisation Regions have pledged to achieve measles elimination. Unfortunately, not all countries and global partners have demonstrated an appropriate commitment to these laudable public health goals, and the negative impact of the COVID-19 pandemic on coverage rates has been profound. Unsurprisingly, large disruptive outbreaks are already occurring in many countries with a global epidemic curve ominously similar to that of 2018/2019 emerging. The Immunization Agenda 2030 will fail dismally unless measles and rubella eradication efforts are accelerated. Over half of all member states have been verified to have eliminated rubella and endemic rubella transmission has not been re-established in any country to date. In 2023, 84 countries and areas were verified to have sustained elimination of measles. However, without a global target, this success will be difficult to sustain. Now is the time for a global eradication goal and commitment by the World Health Assembly. Having a galvanising goal, with a shared call for action, will demand adequate resourcing from every country government and global partners. Greater coordination across countries and regions will be necessary. Measles, rubella and congenital rubella syndrome eradication should not remain just a technically feasible possibility but rather be completed to ensure that future generations of children do not live under the shadow of preventable childhood death and lifelong disability.
摘要：
没有疫苗能更有效地减轻疾病负担，特别是在预防儿童死亡方面，而不是含有麻疹的疫苗。投资回报使麻疹疫苗成为最具成本效益的公共卫生措施之一。详尽的生物学评论，技术,经济和方案证据已经得出结论，麻疹可以而且应该被根除，通过在含麻疹的疫苗中加入风疹抗原，先天性风疹综合症也将被根除。世界卫生组织所有地区都承诺消除麻疹。不幸的是,并非所有国家和全球合作伙伴都表现出对这些值得称赞的公共卫生目标的适当承诺，COVID-19大流行对覆盖率的负面影响是深远的。毫不奇怪,大型破坏性疫情已经在许多国家发生，全球疫情曲线与2018/2019年不祥。除非加快消灭麻疹和风疹的努力，否则《2030年免疫议程》将失败。超过一半的成员国已被证实已经消除了风疹，并且迄今为止尚未在任何国家重新建立风疹流行传播。2023年，84个国家和地区被证实持续消除了麻疹。然而,没有全球目标，这种成功将难以维持。现在是世界卫生大会实现全球根除目标和承诺的时候了。有一个激励目标，共同呼吁采取行动，将要求每个国家政府和全球合作伙伴提供足够的资源。各国和各区域必须加强协调。麻疹,消除风疹和先天性风疹综合症不应该只是技术上可行的可能性，而是应该完成，以确保后代儿童不会生活在可预防的儿童死亡和终身残疾的阴影下。
