PDF(Pubmed)
Abstract：
BACKGROUND: Cancer survivors are at higher risk of developing severe complications from influenza due to their compromised immune systems. Despite their increased vulnerability to influenza and the availability of vaccines, vaccine hesitancy among cancer survivors remains a significant public health concern in China.
METHODS: A multicenter, cross-sectional study was conducted among cancer survivors in China from January to December 2023. A total of 500 participants were recruited from the oncology departments of five tertiary hospitals. A structured, self-administered questionnaire was used to collect data on socio-demographic characteristics, cancer-related information, medical history, lifestyle factors, and influenza vaccine hesitancy. Univariate and multivariate logistic regression analyses were performed to identify factors associated with influenza vaccine hesitancy.
RESULTS: The response rate was 97.0% (485/500). Among all participants, 204 (42.06%) reported vaccine hesitancy. The results of multiple logistic regression showed that the longer the end of anti-cancer treatment, without a history of adverse vaccine reactions, and the level of family support played a protective role in vaccine hesitancy. Current rehabilitation status, frequent colds, not being informed by doctors about vaccination, exercising, lack of community vaccination education programs, and concerns about vaccine safety were risk factors that increase vaccine hesitancy.
CONCLUSIONS: A high proportion of cancer survivors in our study reported influenza vaccine hesitancy. Addressing concerns about vaccine safety, improving access to vaccination services, and enhancing doctor-patient communication are crucial for increasing influenza vaccine uptake in this vulnerable population.
METHODS: A multicenter, cross-sectional study was conducted among cancer survivors in China from January to December 2023. A total of 500 participants were recruited from the oncology departments of five tertiary hospitals. A structured, self-administered questionnaire was used to collect data on socio-demographic characteristics, cancer-related information, medical history, lifestyle factors, and influenza vaccine hesitancy. Univariate and multivariate logistic regression analyses were performed to identify factors associated with influenza vaccine hesitancy.
RESULTS: The response rate was 97.0% (485/500). Among all participants, 204 (42.06%) reported vaccine hesitancy. The results of multiple logistic regression showed that the longer the end of anti-cancer treatment, without a history of adverse vaccine reactions, and the level of family support played a protective role in vaccine hesitancy. Current rehabilitation status, frequent colds, not being informed by doctors about vaccination, exercising, lack of community vaccination education programs, and concerns about vaccine safety were risk factors that increase vaccine hesitancy.
CONCLUSIONS: A high proportion of cancer survivors in our study reported influenza vaccine hesitancy. Addressing concerns about vaccine safety, improving access to vaccination services, and enhancing doctor-patient communication are crucial for increasing influenza vaccine uptake in this vulnerable population.
摘要：
背景：由于免疫系统受损，癌症幸存者患流感严重并发症的风险更高。尽管他们对流感的脆弱性和疫苗的供应增加，在中国，癌症幸存者的疫苗犹豫仍然是一个重大的公共卫生问题。
方法：多中心，在2023年1月至12月的中国癌症幸存者中进行了横断面研究.共有500名参与者从五家三级医院的肿瘤科招募。一个结构化的，自我管理问卷用于收集社会人口统计学特征的数据，癌症相关信息,病史,生活方式因素，和流感疫苗犹豫。进行单变量和多变量逻辑回归分析以确定与流感疫苗犹豫相关的因素。
结果：有效率为97.0%（485/500）。在所有参与者中，204（42.06%）报告疫苗犹豫。多元logistic回归分析结果显示,抗癌治疗结束时间越长,没有疫苗不良反应史，家庭支持水平在疫苗犹豫中发挥了保护作用。目前的康复状况，经常感冒,没有被医生告知疫苗接种，锻炼,缺乏社区疫苗接种教育计划，对疫苗安全性的担忧是增加疫苗犹豫的危险因素。
结论：在我们的研究中，高比例的癌症幸存者报告了流感疫苗犹豫。解决对疫苗安全的担忧，改善获得疫苗接种服务的机会，加强医患沟通对于增加这一脆弱人群的流感疫苗摄入量至关重要。
方法：多中心，在2023年1月至12月的中国癌症幸存者中进行了横断面研究.共有500名参与者从五家三级医院的肿瘤科招募。一个结构化的，自我管理问卷用于收集社会人口统计学特征的数据，癌症相关信息,病史,生活方式因素，和流感疫苗犹豫。进行单变量和多变量逻辑回归分析以确定与流感疫苗犹豫相关的因素。
结果：有效率为97.0%（485/500）。在所有参与者中，204（42.06%）报告疫苗犹豫。多元logistic回归分析结果显示,抗癌治疗结束时间越长,没有疫苗不良反应史，家庭支持水平在疫苗犹豫中发挥了保护作用。目前的康复状况，经常感冒,没有被医生告知疫苗接种，锻炼,缺乏社区疫苗接种教育计划，对疫苗安全性的担忧是增加疫苗犹豫的危险因素。
结论：在我们的研究中，高比例的癌症幸存者报告了流感疫苗犹豫。解决对疫苗安全的担忧，改善获得疫苗接种服务的机会，加强医患沟通对于增加这一脆弱人群的流感疫苗摄入量至关重要。
