PDF(Pubmed)
Abstract：
The interface between material science and ophthalmic medicine is witnessing significant advances with the introduction of biopolymers in medical device fabrication. This review discusses the impact of biopolymers on the development of ophthalmic devices, such as intraocular lenses, stents, and various prosthetics. Biopolymers are emerging as superior alternatives due to their biocompatibility, mechanical robustness, and biodegradability, presenting an advance over traditional materials with respect to patient comfort and environmental considerations. We explore the spectrum of biopolymers used in ophthalmic devices and evaluate their physical properties, compatibility with biological tissues, and clinical performances. Specific applications in oculoplastic and orbital surgeries, hydrogel applications in ocular therapeutics, and polymeric drug delivery systems for a range of ophthalmic conditions were reviewed. We also anticipate future directions and identify challenges in the field, advocating for a collaborative approach between material science and ophthalmic practice to foster innovative, patient-focused treatments. This synthesis aims to reinforce the potential of biopolymers to improve ophthalmic device technology and enhance clinical outcomes.
摘要：
随着生物聚合物在医疗设备制造中的引入，材料科学与眼科医学之间的接口正在取得重大进展。这篇综述讨论了生物聚合物对眼科设备发展的影响，如人工晶状体，支架,和各种假肢。生物聚合物由于其生物相容性而成为卓越的替代品，机械坚固性，和生物降解性，在患者舒适度和环境因素方面，比传统材料有所进步。我们探索眼科设备中使用的生物聚合物的光谱，并评估其物理性质，与生物组织的相容性，和临床表现。眼整形和眼眶手术的具体应用，水凝胶在眼部治疗中的应用，和聚合物药物递送系统的一系列眼科条件进行了审查。我们还预测未来的方向并确定该领域的挑战，倡导材料科学和眼科实践之间的合作方法，以促进创新，以患者为中心的治疗。该合成旨在增强生物聚合物改善眼科装置技术和增强临床结果的潜力。
