PDF(Pubmed)
Abstract：
Nowadays, bacteria resistance to many antibiotics is a huge problem, especially in clinics and other parts of the healthcare system. This critical health issue requires a dynamic approach to produce new types of antibacterial coatings to combat various pathogen microbes. In this research, we prepared a new type of carbon quantum dots based on phloroglucinol using the bottom-up method. Polyurethane composite films were produced using the swell-encapsulation-shrink method. Detailed electrostatic force and viscoelastic microscopy of carbon quantum dots revealed inhomogeneous structure characterized by electron-rich/soft and electron-poor/hard regions. The uncommon photoluminescence spectrum of carbon quantum dots core had a multipeak structure. Several tests confirmed that carbon quantum dots and composite films produced singlet oxygen. Antibacterial and antibiofouling efficiency of composite films was tested on eight bacteria strains and three bacteria biofilms.
摘要：
如今,细菌对许多抗生素的耐药性是一个巨大的问题，特别是在诊所和医疗保健系统的其他部分。这一关键的健康问题需要一种动态的方法来生产新型的抗菌涂料，以对抗各种病原体微生物。在这项研究中,采用自下而上的方法制备了一种基于间苯三酚的新型碳量子点。使用溶胀-封装-收缩方法生产聚氨酯复合膜。碳量子点的详细静电力和粘弹性显微镜显示出不均匀的结构，其特征在于富电子/软和贫电子/硬区域。碳量子点核心的不常见光致发光光谱具有多峰结构。一些测试证实碳量子点和复合膜产生单线态氧。在八种细菌菌株和三种细菌生物膜上测试了复合膜的抗菌和抗生物污染效率。
