PDF(Pubmed)
Abstract：
Cancer treatment is a significant focus in medicine, owing to the increasing global incidence of cancers. Patients with advanced cancers that do not respond to conventional therapies have limited options and an unfavorable prognosis. Consequently, researchers are investigating complementary approaches to conventional treatments. One such approach is alkalization therapy, which aims to neutralize the acidic tumor microenvironment (TME) by increasing its pH level. The acidic TME promotes inflammation, tumor progression, and drug resistance. Alkalization therapy has been demonstrated to be effective for various cancers. In addition, natural products, such as triterpenoids, parthenolides, fulvic acid, Taxus yunnanensis, and apple pectin have the potential to alleviate symptoms, maintain physical fitness, and improve treatment outcomes of cancer patients through their anti-inflammatory, antioxidant, and anticancer properties. In this review, we focus on the effects of alkalization therapy and natural products on cancer. Furthermore, we present a case series of advanced cancer patients who received alkalization therapy and natural products alongside standard treatments, resulting in long-term survival. We posit that alkalization therapy together with supplementation with natural products may confer benefits to cancer patients, by mitigating the side effects of chemotherapy and complementing standard treatments. However, further research is warranted to validate these clinical findings.
摘要：
癌症治疗是医学中的一个重要焦点，由于全球癌症发病率的增加。对常规疗法无反应的晚期癌症患者的选择有限且预后不利。因此,研究人员正在研究传统治疗的补充方法。其中一种方法是碱化治疗，其旨在通过增加其pH水平来中和酸性肿瘤微环境(TME)。酸性TME促进炎症，肿瘤进展，和抗药性。碱化疗法已被证明对各种癌症有效。此外,天然产品,如三萜类化合物，小白菊,富里酸，云南红豆杉,苹果果胶有可能缓解症状，保持身体健康，并通过抗炎改善癌症患者的治疗结果，抗氧化剂，和抗癌特性。在这次审查中,我们专注于碱化疗法和天然产物对癌症的影响。此外，我们介绍了一系列接受碱化治疗和天然产品以及标准治疗的晚期癌症患者，导致长期生存。我们认为碱化疗法与天然产物的补充可能会给癌症患者带来好处，通过减轻化疗的副作用和补充标准治疗。然而,需要进一步的研究来验证这些临床发现.
