PDF(Pubmed)
Abstract：
Motivated by the culinary and ethnopharmacological use of Acmella oleracea (L.) R.K. Jansen, this study aimed to unveil new chemical compounds from its essential oil (EO). Acmella oleracea, known for its anesthetic and spicy properties, has been used in traditional medicine and cuisine, particularly in Northern Brazil. Through a detailed GC-MS analysis, 180 constituents were identified, including 12 tentatively identified long-chain α-keto esters of various acids. Additionally, 18 new esters were synthesized for structural verification. This research expands the known chemical diversity of A. oleracea EO, providing a basis for potential pharmacological applications. The identification of new natural products, including homologs and analogs of acmellonate, underscores the EO\'s rich chemical profile and its potential for novel bioproduct development.
摘要：
受菊苣的烹饪和民族药理学使用的动机（L.)R.K.詹森，这项研究旨在从其精油（EO）中揭示新的化合物。Acmellaoleracea,以其麻醉和辛辣特性而闻名，已用于传统医学和烹饪，特别是在巴西北部。通过详细的GC-MS分析,鉴定了180种成分，包括12种初步鉴定的各种酸的长链α-酮酯。此外,合成了18种新酯进行结构验证。这项研究扩展了已知的A.oleraceaEO的化学多样性，为潜在的药理学应用提供基础。新的天然产品的鉴定，包括acmellonate的同系物和类似物，强调了EO丰富的化学特性及其在新型生物产品开发中的潜力。
