关键词: Echinophora novel drugs phytopharmaceuticals traditional medicine

来  源:   DOI:10.3390/plants13121599   PDF(Pubmed)

Abstract:
Species belonging to the genus Echinophora (Apiaceae) have been used by humanity since ancient times as flavoring agents, preservatives, and medicines for the treatment of a broad spectrum of conditions, including respiratory, digestive and kidney disorders, fungi infections, wounds, and gastric ulcers. Phytochemical studies on this botanical genus mainly investigate the essential oil composition and reveal the species as a rich source of volatile compounds, including monoterpenes and phenylpropanoids. Among the non-volatile secondary metabolites, flavonoids, coumarins, phenolic acids, phytosterols, and polyacetylenes have been identified. Pharmacological studies revealed Echinophora extracts and essential oils exhibit different biological properties, including antibacterial, antifungal, anticancer, insecticidal, anti-inflammatory, and hepatoprotective activities. However, compared to other genera, the biological activity and chemical diversity of this genus are not well studied. In future decades, it is highly likely that the small genus Echinophora will play an important role in drug discovery and drug development.
摘要:
自古以来,人类就一直使用属于Echinophora属(Apiaceae)的物种作为调味剂,防腐剂,以及治疗各种疾病的药物,包括呼吸,消化系统和肾脏疾病,真菌感染,伤口,还有胃溃疡.对该植物属的植物化学研究主要调查精油成分,并揭示该物种是挥发性化合物的丰富来源,包括单萜和苯丙素类。在非挥发性次级代谢物中,黄酮类化合物,香豆素,酚酸,植物甾醇,和聚乙炔已经确定。药理研究表明,棘豆提取物和精油表现出不同的生物学特性,包括抗菌,抗真菌药,抗癌,杀虫,抗炎,和肝保护活动。然而,与其他属相比,该属的生物活性和化学多样性尚未得到很好的研究。在未来的几十年里,这是极有可能的,小属的Echinophora将发挥重要作用,在药物发现和药物开发。
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