PDF(Pubmed)
Abstract：
The Lamiaceae family, which includes several well-known aromatic plants, is scientifically relevant due to its essential oils (EOs). In this work, four EOs from Mediterranean species, namely Origanum vulgare L., Rosmarinus officinalis L., Salvia officinalis L., and Thymus vulgaris L., were evaluated for their volatile profiles and the biological activity in vitro to assess their potential use in the food and cosmetic sector. GC/MS analysis revealed dominant compounds, such as carvacrol, thymol, and eucalyptol. Regarding biological action, the samples exhibited antioxidant, cytotoxic, anti-inflammatory, antimicrobial, and antifungal activities, with O. vulgare and T. officinalis standing out. T. vulgaris showed the lowest EC50 in the reducing power assay, and O. vulgare had the lowest EC50 in the DPPH assay. Most EOs also displayed excellent anti-inflammatory responses and antifungal properties, with O. vulgare and T. vulgaris also demonstrating antibacterial activity. All EOs from Mediterranean species showed cytotoxicity against tumoral cell lines. Overall, the selected EOs stood out for their interesting bioactivities, with the obtained results underscoring their potential as natural preservatives and bioactive agents in various industrial applications, including food, pharmaceuticals, and cosmetics.
摘要：
唇形科，其中包括几种著名的芳香植物，由于其精油（EO）而具有科学意义。在这项工作中,来自地中海物种的四个EO，即牛至，迷迭香，丹参，和胸腺，评估其挥发性特征和体外生物活性，以评估其在食品和化妆品领域的潜在用途。GC/MS分析显示主要化合物，比如香芹酚,百里酚,还有桉树精.关于生物作用，样品表现出抗氧化剂，细胞毒性，抗炎,抗菌，和抗真菌活性，O.vulgare和T.officinalis脱颖而出。T.vulgaris在还原功率测定中显示出最低的EC50，在DPPH测定中，和O.vulgare的EC50最低。大多数EO还表现出优异的抗炎反应和抗真菌特性，O.vulgare和T.vulgaris也表现出抗菌活性。来自地中海物种的所有EO均显示出对肿瘤细胞系的细胞毒性。总的来说,选定的EO因其有趣的生物活动而脱颖而出，获得的结果强调了它们在各种工业应用中作为天然防腐剂和生物活性剂的潜力，包括食物,制药，和化妆品。
