PDF(Pubmed)
Abstract：
Diarrheal diseases caused by enteric pathogens are a significant public health concern. It is widely considered that close contact between persons, poor hygiene, and consumption of contaminated food are the primary causes of gastroenteritis. Clinical microbiology laboratory observations indicate that the incidence of enteropathogenic microorganisms may have been reduced in Denmark during the COVID-19 pandemic. All Departments of Clinical Microbiology in Denmark provided data on the monthly incidence of Salmonella spp., Escherichia coli, Campylobacter spp., Clostridioides difficile, Norovirus GI+GII, Giardia duodenalis, and Cryptosporidium from March 2018 to February 2021. The data were divided into three periods as follows: Control Period 1 (March 2018 to February 2019); Control Period 2 (March 2019 to February 2020); and the Restriction (pandemic) Period (March 2020 to February 2021). The incidences of pathogenic Salmonella spp.-, Escherichia coli-, and Campylobacter spp.-positive samples decreased by 57.3%, 48.1%, and 32.9%, respectively, during the restriction period. No decrease in C. difficile was observed. Norovirus GI+GII-positive samples decreased by 85.6%. Giardia duodenalis-positive samples decreased by 66.2%. Cryptosporidium species decreased by 59.6%. This study demonstrates a clear decrease in the incidence of enteropathogenic bacteria (except for C. difficile), viruses, and parasites during the SARS-CoV-2 restriction period in Denmark.
摘要：
由肠道病原体引起的腹泻疾病是重要的公共卫生问题。人们普遍认为，人与人之间的密切接触，卫生条件差,食用受污染的食物是胃肠炎的主要原因。临床微生物学实验室观察表明，在COVID-19大流行期间，丹麦的肠病原微生物的发生率可能有所降低。丹麦所有临床微生物学部门都提供了沙门氏菌的每月发病率数据。,大肠杆菌,弯曲杆菌属。,艰难梭菌，诺如病毒GI+GII,十二指肠贾第虫,和隐孢子虫，从2018年3月到2021年2月。数据分为以下三个时期：控制期1（2018年3月至2019年2月）；控制期2（2019年3月至2020年2月）；和限制（大流行）期（2020年3月至2021年2月）。致病性沙门氏菌的发病率。-大肠杆菌-，和弯曲杆菌。-阳性样本减少57.3%，48.1%,和32.9%，分别,在限制期间。没有观察到艰难梭菌的减少。诺如病毒GI+GII阳性样本减少85.6%。十二指肠贾第鞭毛虫阳性样本减少66.2%。隐孢子虫物种减少了59.6％。这项研究表明，肠致病性细菌（艰难梭菌除外）的发生率明显降低，病毒,和寄生虫在丹麦的SARS-CoV-2限制期。
