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Abstract：
Background: To determine the differences in the effects of intense pulsed light (IPL) treatment when including the upper and lower lid or lateral canthus area in patients with meibomian gland dysfunction (MGD). Methods: Patients who underwent three IPL treatment sessions at 3-week intervals were divided into three groups according to the treatment sites: group A, lower lid; group B, upper and lower lids; and group C, lower lid and lateral canthal area. Before and after the IPL treatment sessions, we obtained the lid abnormality score (LAS), meibum expressibility (ME), meibum quality (MQ), lipid layer thickness (LLT), type I Schirmer test (ST), tear break-up time (TBUT) test, corneal fluorescein staining scores (CFSs), and Ocular Surface Disease Index (OSDI). Results: IPL treatment significantly improved LASs, ME, MQ, TBUT, CFS, and OSDI values in all groups. Differences in LAS values before and after IPL treatment were significantly greater in groups B and C than those in group A. Conclusions: IPL treatment encompassing the upper lid and lateral canthus together with the lower lid elicited additional improvement in patients with MGD. The additional effect on treating the lateral canthus was similar to the effect observed on the additional treatment of the upper lid.
摘要：
背景：确定在睑板腺功能障碍（MGD）患者中，包括上眼睑和下眼睑或外侧can区域时，强脉冲光（IPL）治疗效果的差异。方法：每隔3周接受3次IPL治疗的患者根据治疗部位分为3组：A组，下盖；B组，上盖和下盖；和C组，下眼睑和外侧than区。在IPL治疗之前和之后，我们获得了眼睑异常评分(LAS)，美布表现力(ME)，美布质量(MQ)，脂质层厚度（LLT），I型Schirmer试验(ST),撕裂破裂时间(TBUT)测试,角膜荧光素染色评分（CFSs），和眼表疾病指数（OSDI）。结果:IPL治疗显著改善LASs,我,MQ,TBUT,CFS,和所有组中的OSDI值。B组和C组IPL治疗前后LAS值的差异明显大于A组。结论：包括上眼睑和下眼睑的IPL治疗可使MGD患者得到进一步改善。对治疗侧眼角的额外作用类似于对上眼睑的额外治疗所观察到的作用。
