PDF(Pubmed)
Abstract：
We aimed to examine the prevalence of, and factors associated with, quality of life (QOL) worsening among coronavirus disease 2019 (COVID-19) survivors. This population-based retrospective cohort study used data from the Korea Disease Control and Prevention Agency and the National Health Insurance Service in South Korea. A total of 325,666 COVID-19 survivors were included in this study. Among them, 106,091 (32.6%) survivors experienced worsening QOL after COVID-19. Specifically, 21,223 (6.5%) participants experienced job loss, 94,556 (29.0%) experienced decreased household income, and 559 (0.2%) acquired new disabilities. In the multivariable logistic regression model, living in rural areas (odds ratio [OR]: 1.02; 95% confidence interval [CI]: 1.01, 1.04; p = 0.009), intensive care unit admission (OR: 1.08, 95% CI: 1.02, 1.15; p = 0.028), and increase in self-payment by 100 USD (OR: 1.02, 95% CI: 1.02, 1.02; p < 0.001) were associated with increased QOL worsening after COVID-19. Old age (OR: 0.99, 95% CI: 0.98, 0.99; p < 0.001), first vaccination (OR: 0.89, 95% CI: 0.86, 0.93; p < 0.001), and second vaccination (OR: 0.95, 95% CI: 0.93, 0.96; p < 0.001) were associated with decreased QOL worsening after COVID-19. Approximately one-third of COVID-19 survivors in South Korea who were admitted to hospitals or monitoring centers experienced QOL worsening.
摘要：
我们的目的是检查患病率，以及与之相关的因素，2019年冠状病毒病（COVID-19）幸存者的生活质量（QOL）恶化。这项基于人群的回顾性队列研究使用了韩国疾病控制与预防局和韩国国家健康保险局的数据。本研究共纳入325,666名COVID-19幸存者。其中,106,091人（32.6%）幸存者在COVID-19后经历了生活质量恶化。具体来说,21,223（6.5％）参与者经历了失业，94556(29.0%)家庭收入下降，559人(0.2%)获得新残疾。在多变量逻辑回归模型中，生活在农村地区(比值比[OR]：1.02；95%置信区间[CI]：1.01，1.04；p=0.009)，重症监护病房入院（OR：1.08，95%CI：1.02，1.15；p=0.028），自我付款增加100美元（OR：1.02，95%CI：1.02，1.02；p<0.001）与COVID-19后生活质量恶化增加有关。老年（OR：0.99，95%CI：0.98，0.99；p<0.001），首次接种疫苗（OR：0.89，95%CI：0.86，0.93；p<0.001），和第二次疫苗接种(OR：0.95，95%CI：0.93，0.96；p<0.001)与COVID-19后生活质量恶化降低相关。在韩国，大约三分之一的COVID-19幸存者被送往医院或监测中心，经历了生活质量恶化。
