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Abstract：
The shift towards personalized cancer medicine (PCM) represents a significant transformation in cancer care, emphasizing tailored treatments based on the genetic understanding of cancer at the cellular level. This review draws on recent literature to explore key factors influencing PCM implementation, highlighting the role of innovative leadership, interdisciplinary collaboration, and coordinated funding and regulatory strategies. Success in PCM relies on overcoming challenges such as integrating diverse medical disciplines, securing sustainable investment for shared infrastructures, and navigating complex regulatory landscapes. Effective leadership is crucial for fostering a culture of innovation and teamwork, essential for translating complex biological insights into personalized treatment strategies. The transition to PCM necessitates not only organizational adaptation but also the development of new professional roles and training programs, underscoring the need for a multidisciplinary approach and the importance of team science in overcoming the limitations of traditional medical paradigms. The conclusion underscores that PCM\'s success hinges on creating collaborative environments that support innovation, adaptability, and shared vision among all stakeholders involved in cancer care.
摘要：
向个性化癌症医学（PCM）的转变代表了癌症护理的重大转变，强调基于细胞水平对癌症的遗传理解的定制治疗。这篇综述借鉴了最近的文献，探讨了影响PCM实施的关键因素，突出创新领导力的作用，跨学科合作,以及协调的资金和监管战略。PCM的成功依赖于克服挑战，例如整合不同的医学学科，确保共享基础设施的可持续投资，导航复杂的监管环境。有效的领导对于培养创新和团队合作文化至关重要，对于将复杂的生物学见解转化为个性化治疗策略至关重要。向PCM的过渡不仅需要组织适应，还需要开发新的专业角色和培训计划，强调了多学科方法的必要性以及团队科学在克服传统医学范式局限性方面的重要性。结论强调PCM的成功取决于创建支持创新的协作环境，适应性，以及参与癌症护理的所有利益相关者之间的共同愿景。
