PDF(Pubmed)
Abstract：
BACKGROUND: Sarcoidosis, characterized by non-caseating epithelioid granulomas, presents diagnostic and therapeutic challenges.
METHODS: Here we present a 38-year-old woman who exhibited erythematous and infiltrated skin lesions on her facial region following fractional laser treatment.
RESULTS: Histological analysis confirmed cutaneous sarcoidosis. Initial interventions with topical clobetasol and oral chloroquine provided transient relief. Subsequent outpatient management comprised topical tacrolimus and clobetasol, as well as systemic methotrexate, later substituted with prednisone. Gradual tapering resulted in lesion reduction.
CONCLUSIONS: This case underscores the intricate nature of cutaneous sarcoidosis and the necessity for personalized therapeutic approaches. The association with cosmetic procedures highlights the importance of understanding potential triggers. The presented case highlights and reminds the medical community that lasers are not only used for therapeutic purposes but can also induce specific responses through laser therapy. Notably, while laser therapy is frequently employed in treating cutaneous sarcoidosis, its role in inducing sarcoidosis warrants further investigation.
METHODS: Here we present a 38-year-old woman who exhibited erythematous and infiltrated skin lesions on her facial region following fractional laser treatment.
RESULTS: Histological analysis confirmed cutaneous sarcoidosis. Initial interventions with topical clobetasol and oral chloroquine provided transient relief. Subsequent outpatient management comprised topical tacrolimus and clobetasol, as well as systemic methotrexate, later substituted with prednisone. Gradual tapering resulted in lesion reduction.
CONCLUSIONS: This case underscores the intricate nature of cutaneous sarcoidosis and the necessity for personalized therapeutic approaches. The association with cosmetic procedures highlights the importance of understanding potential triggers. The presented case highlights and reminds the medical community that lasers are not only used for therapeutic purposes but can also induce specific responses through laser therapy. Notably, while laser therapy is frequently employed in treating cutaneous sarcoidosis, its role in inducing sarcoidosis warrants further investigation.
摘要：
背景：结节病，以非干酪性上皮样肉芽肿为特征，提出了诊断和治疗的挑战。
方法：这里我们介绍了一名38岁的女性，她在点阵激光治疗后面部区域出现红斑和浸润的皮肤损伤。
结果：组织学分析证实皮肤结节病。局部氯倍他索和口服氯喹的初始干预提供了短暂的缓解。随后的门诊管理包括外用他克莫司和氯倍他索，以及全身性甲氨蝶呤，后来用泼尼松替代。逐渐变细导致病变减少。
结论：该病例强调了皮肤结节病的复杂性和个性化治疗方法的必要性。与整容手术的关联突出了理解潜在触发因素的重要性。所呈现的病例突出并提醒医学界，激光不仅用于治疗目的，而且还可以通过激光治疗引起特定反应。值得注意的是,虽然激光治疗经常用于治疗皮肤结节病，其在诱导结节病中的作用值得进一步研究。
方法：这里我们介绍了一名38岁的女性，她在点阵激光治疗后面部区域出现红斑和浸润的皮肤损伤。
结果：组织学分析证实皮肤结节病。局部氯倍他索和口服氯喹的初始干预提供了短暂的缓解。随后的门诊管理包括外用他克莫司和氯倍他索，以及全身性甲氨蝶呤，后来用泼尼松替代。逐渐变细导致病变减少。
结论：该病例强调了皮肤结节病的复杂性和个性化治疗方法的必要性。与整容手术的关联突出了理解潜在触发因素的重要性。所呈现的病例突出并提醒医学界，激光不仅用于治疗目的，而且还可以通过激光治疗引起特定反应。值得注意的是,虽然激光治疗经常用于治疗皮肤结节病，其在诱导结节病中的作用值得进一步研究。
