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Abstract：
Electrophysiological studies have long established themselves as reliable methods for assessing the functional state of the brain and spinal cord, the degree of neurodegeneration, and evaluating the effectiveness of therapy. In addition, they can be used to diagnose, predict functional outcomes, and test the effectiveness of therapeutic and rehabilitation programs not only in clinical settings, but also at the preclinical level. Considering the urgent need to develop potential stimulators of neuroregeneration, it seems relevant to obtain objective data when modeling neurological diseases in animals. Thus, in the context of the application of electrophysiological methods, not only the comparison of the basic characteristics of bioelectrical activity of the brain and spinal cord in humans and animals, but also their changes against the background of neurodegenerative and post-traumatic processes are of particular importance. In light of the above, this review will contribute to a better understanding of the results of electrophysiological assessment in neurodegenerative and post-traumatic processes as well as the possibility of translating these methods from model animals to humans.
摘要：
长期以来，电生理学研究已将其确立为评估大脑和脊髓功能状态的可靠方法。神经变性的程度，并评估治疗的有效性。此外,它们可以用来诊断，预测功能结果，不仅在临床环境中测试治疗和康复计划的有效性，而且在临床前水平。考虑到迫切需要开发潜在的神经再生刺激器，在模拟动物神经疾病时，获得客观数据似乎是相关的。因此，在电生理学方法的应用中，不仅比较了人类和动物大脑和脊髓生物电活动的基本特征，而且它们在神经退行性和创伤后过程背景下的变化也特别重要。鉴于上述情况，这篇综述将有助于更好地理解神经退行性和创伤后过程的电生理评估结果，以及将这些方法从模型动物转化为人类的可能性。
