PDF(Pubmed)
Abstract：
Multiple Sclerosis (MS) is a demyelinating and chronic disease with variable neurological symptoms. There are different scales that score the level of disability, but only few papers have taken into consideration the 5-times sit-to-stand (5STS) test and the 30 s chair stand test (30CST), which are valid and easily obtainable indicators of other neurological diseases. The aim of our research is to verify the validity, reproducibility, and responsiveness of these tests. Patients afflicted with MS were enrolled in the AISM outpatient facility. The inclusion criterion was an EDSS score less than 6.5. We performed the 5STS, 30CST, and timed 25-foot walk (T25-FW) tests and recorded EDSS scores in the first evaluation. Then, we recorded the performance after 5 days (conducted by a second blind operator to ensure test-retest reproducibility), and the last evaluation was made after 12 sessions of physiotherapy. We recruited 38 patients diagnosed with MS. The results show significant data regarding validity, reproducibility, and responsiveness for both scales. The data argue in favor of adding these tests to the relevant clinical assessments. These two tests are simple, reliable, and easy to administer, and the data confirm that they can be included in the evaluation of patients with MS.
摘要：
多发性硬化(MS)是一种具有可变神经症状的脱髓鞘和慢性疾病。残疾程度的评分有不同的量表，但是只有少数论文考虑了5次坐立测试（5STS）和30s椅架测试（30CST），这是其他神经系统疾病的有效和容易获得的指标。我们研究的目的是验证其有效性，再现性，和这些测试的响应性。患有MS的患者被纳入AISM门诊设施。纳入标准是EDSS评分小于6.5。我们执行了5STS,30CST,和定时25英尺步行（T25-FW）测试，并在第一次评估中记录EDSS得分。然后，我们记录了5天后的性能（由第二个盲人操作员进行，以确保测试-重测的可重复性），最后一次评估是在12次物理治疗后进行的。我们招募了38名诊断为MS的患者。结果表明，有关有效性的重要数据，再现性，和两个量表的反应能力。数据支持将这些测试添加到相关的临床评估中。这两个测试很简单，可靠,易于管理，数据证实它们可以包括在MS患者的评估中。
