关键词: cafestol cardiovascular diseases endothelial function inflammation lipid metabolism

Mesh : Humans Cardiovascular Diseases Coffee Lipid Metabolism / drug effects

来  源:   DOI:10.3390/medicina60060867   PDF(Pubmed)

Abstract:
Cafestol, a bioactive compound found in coffee, has attracted considerable attention due to its potential impact on cardiovascular health. This review aims to comprehensively explore the association between cafestol and cardiovascular diseases. We delve into the mechanisms through which cafestol influences lipid metabolism, inflammation, and endothelial function, all of which are pivotal in cardiovascular pathophysiology. Moreover, we meticulously analyze epidemiological studies and clinical trials to elucidate the relationship between cafestol and cardiovascular outcomes. Through a critical examination of existing literature, we aim to provide insights into the potential benefits and risks associated with cafestol concerning cardiovascular health.
摘要:
Cafestol,咖啡中的生物活性化合物,由于其对心血管健康的潜在影响,已经引起了相当大的关注。本文旨在全面探讨cafestol与心血管疾病之间的关系。我们深入研究了咖啡醇影响脂质代谢的机制,炎症,和内皮功能,所有这些都是心血管病理生理学的关键。此外,我们对流行病学研究和临床试验进行了细致分析,以阐明cafestol与心血管结局之间的关系.通过对现有文献的批判性考察,我们的目标是提供与cafestol有关的心血管健康的潜在益处和风险的见解。
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