关键词: DLBCL transformation MALT lymphoma histologic transformation primary pulmonary lymphoma

Mesh : Humans Lymphoma, B-Cell, Marginal Zone / therapy Lymphoma, Large B-Cell, Diffuse / pathology therapy Lung Neoplasms / pathology diagnostic imaging therapy Male Middle Aged

来  源:   DOI:10.3390/medicina60060840   PDF(Pubmed)

Abstract:
Primary pulmonary lymphoma is a rare neoplasm characterized by the proliferation of lymphoid tissue affecting the lungs. The most common subtype is marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT). Rarely, a MALT lymphoma transforms into a diffuse large B-cell lymphoma (DLBCL). Treatment options include chemotherapy, radiotherapy, immunotherapy, and surgery. Here, we describe a patient with a primary pulmonary MALT lymphoma transforming into DLBCL. The purpose of this case report is to raise awareness of the relevant clinical and imaging features and to emphasize the need for a multidisciplinary approach to optimal management. In addition, we screened the PubMed and Embase databases for similar reports with a confirmed presence of transforming lymphoma within the lungs.
摘要:
原发性肺淋巴瘤是一种罕见的肿瘤,其特征是影响肺的淋巴组织增殖。最常见的亚型是粘膜相关淋巴组织边缘区淋巴瘤(MALT)。很少,MALT淋巴瘤转变为弥漫性大B细胞淋巴瘤(DLBCL)。治疗方案包括化疗,放射治疗,免疫疗法,和手术。这里,我们描述了一名原发性肺MALT淋巴瘤转化为DLBCL的患者。本病例报告的目的是提高对相关临床和影像学特征的认识,并强调需要采用多学科方法来优化管理。此外,我们在PubMed和Embase数据库中筛选了类似的报告,证实肺部存在转化性淋巴瘤.
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