PDF(Pubmed)
Abstract：
This study aimed to estimate the average inbreeding coefficient in Slovak Simmental dairy cattle and evaluate the effect of inbreeding on the length of productive life. All pedigrees included 463,282 animals dating back to 1914. The inbreeding coefficients for each animal in the pedigree were computed using the software CFC 1.0. Length of productive life (LPL) was defined as the time (days) from the first calving to culling, death, or censoring. The influence of inbreeding on the length of productive life was calculated and tested using the Weibull proportional hazards model. The average inbreeding coefficient, the average number of discrete generation equivalents, and the average longest ancestral path for inbred animals were 0.01, 6.59, and 13.08, respectively. While the largest decrease in the mean coefficient of inbreeding was observed from the year of birth 1995 (F = 1.50%) to 2001 (F = 0.59%), an increasing trend of inbreeding in the population was found from 2003 onwards. A weak but significant effect of inbreeding on the length of productive life of Simmental cows was confirmed using survival analysis.
摘要：
本研究旨在估算斯洛伐克西门塔尔奶牛的平均近交系数，并评估近交对生产寿命的影响。所有家谱都包括可追溯到1914年的463,282只动物。使用软件CFC1.0计算家系中每只动物的近交系数。生产寿命长度（LPL）定义为从第一次产卵到剔除的时间（天），死亡,或审查。使用Weibull比例风险模型计算并检验了近亲繁殖对生产寿命的影响。平均近亲繁殖系数，离散代当量的平均数量，近交动物的平均最长祖先路径分别为0.01、6.59和13.08。虽然从1995年出生年份（F=1.50％）到2001年（F=0.59％），近亲繁殖的平均系数下降最大，从2003年开始，人口近亲繁殖的趋势有所增加。使用生存分析证实了近亲繁殖对西门塔尔牛生产寿命的影响微弱但显着。
