PDF(Pubmed)
Abstract：
This study assessed the analgesic and motor effects of the GIN-TONIC block, a combination of the greater ischiatic notch plane block and the caudal lateral quadratus lumborum block, in 24 dogs undergoing pelvic limb surgery. Dogs were randomly divided into two equal groups: GA received acepromazine [(20 µg kg-1 intravenously (IV)] as premedication, and GD received dexmedetomidine (2 µg kg-1 IV). General anesthesia was maintained with isoflurane, and both groups received a GIN-TONIC block using 2% lidocaine. Nociception during surgery and postoperative pain [assessed using the Glasgow Composite Measure Pain Score (GCMPS-SF)] were assessed. Fentanyl (2 µg kg-1 IV) was administered if nociception was noted and morphine (0.5 mg kg-1 IV) was administered during recovery if the pain scores exceeded the predefined threshold. Motor function was assessed during the recovery period using descriptors previously reported. All dogs received analgesics at the 4 h mark before being discharged. Three and two dogs in GD and GA required fentanyl once. Postoperative pain scores remained ≤4/20 for all dogs except one. Dogs achieved non-ataxic ambulation within 38.9 ± 10.3 and 35.1 ± 11.1 min after extubation in GD and GA, respectively. This study highlighted the potential of the GIN-TONIC block as a feasible regional anesthesia method for delivering perioperative analgesia in dogs undergoing pelvic limb orthopedic surgery.
摘要：
这项研究评估了GIN-TONIC阻滞的镇痛和运动作用，大坐骨切迹平面阻滞和腰侧方肌阻滞的组合，在24只接受骨盆肢体手术的狗中。狗被随机分为两个相等的组：GA接受乙酰丙嗪[（静脉注射20µgkg-1（IV）]作为术前用药，GD接受右美托咪定（2µgkg-1IV）。全身麻醉用异氟烷维持，两组均接受2%利多卡因的GIN-TONIC阻滞.评估手术期间的疼痛感受和术后疼痛[使用格拉斯哥综合测量疼痛评分（GCMPS-SF）评估]。如果注意到伤害感受，则给予芬太尼（2µgkg-1IV），如果疼痛评分超过预定阈值，则在恢复期间给予吗啡（0.5mgkg-1IV）。使用先前报道的描述符评估恢复期间的运动功能。所有狗在出院前4小时接受镇痛药。GD和GA中的三只和两只狗需要芬太尼一次。除一只狗外，所有狗的术后疼痛评分均≤4/20。狗在GD和GA拔管后38.9±10.3和35.1±11.1分钟内实现非共济失调下床活动，分别。这项研究强调了GIN-TONIC阻滞作为一种可行的区域麻醉方法的潜力，可在接受骨盆肢体骨科手术的狗中提供围手术期镇痛。
