PDF(Pubmed)
Abstract：
The hypothesis of this randomized controlled trial was that a clinical decision support system (CDSS) would increase adherence to the Mediterranean diet (MD) among adolescent females with polycystic ovary syndrome (PCOS). The objective was to assess the impact of personalized MD plans delivered via a CDSS on nutritional status and psychological well-being. Forty adolescent females (15-17 years) with PCOS were randomly assigned to the MD group (n = 20) or the Control group (n = 20). The MD group received personalized MD plans every 15 days via a CDSS, while the Control group received general nutritional advice. Assessments were conducted at baseline and after 3 months. Results showed significantly increased MD adherence in the MD group compared to the Control group (p < 0.001). The MD group exhibited lower intakes of energy, total fat, saturated fat, and cholesterol, and higher intakes of monounsaturated fat and fiber (p < 0.05). Serum calcium and vitamin D status (p < 0.05), as well as anxiety (p < 0.05) were improved. In conclusion, tailored dietary interventions based on MD principles, delivered via a CDSS, effectively manage PCOS in adolescent females. These findings highlight the potential benefits of using technology to promote dietary adherence and improve health outcomes in this population. ClinicalTrials.gov registry: NCT06380010.
摘要：
这项随机对照试验的假设是，临床决策支持系统（CDSS）将增加患有多囊卵巢综合征（PCOS）的青春期女性对地中海饮食（MD）的依从性。目的是评估通过CDSS提供的个性化MD计划对营养状况和心理健康的影响。将40名患有PCOS的青春期女性（15-17岁）随机分配到MD组（n=20）或对照组（n=20）。MD小组每15天通过CDSS收到个性化的MD计划，对照组接受一般营养建议。在基线和3个月后进行评估。结果显示,与对照组相比,MD组的MD依从性显著增加(p<0.001)。MD组的能量摄入量较低，总脂肪,饱和脂肪,和胆固醇，单不饱和脂肪和纤维摄入量较高(p<0.05)。血清钙和维生素D状态（p<0.05），以及焦虑（p<0.05）得到改善。总之,根据MD原则量身定制的饮食干预措施，通过CDSS交付，有效管理青春期女性的PCOS。这些发现强调了使用技术来促进该人群的饮食依从性和改善健康结果的潜在好处。ClinicalTrials.gov注册表：NCT06380010。
