关键词: asthma children diagnosis follow-up phenotypes therapy

来  源:   DOI:10.3390/children11060632   PDF(Pubmed)

Abstract:
Asthma is a chronic lung disease characterized by reversible bronchoconstriction and inflammation of the bronchi. Its increasing prevalence in childhood as well as different triggers make asthma a challenging disease in several ways: defining its phenotype/endotype, the diagnostic approach (especially in younger children), therapeutic options, and systematic follow-up. Considering these problems, this review approaches the current status and limitations of guidelines used for asthma management in children. It also emphasizes the key points which could lead to a better understanding and the direction to take in future studies.
摘要:
哮喘是一种慢性肺病,其特征在于可逆的支气管收缩和支气管炎症。它在儿童期的患病率增加以及不同的触发因素使哮喘在几个方面成为具有挑战性的疾病:定义其表型/内型,诊断方法(尤其是在年幼的儿童中),治疗选择,和系统的后续行动。考虑到这些问题,本文综述了儿童哮喘管理指南的现状和局限性.它还强调了可能导致更好的理解和未来研究的方向的关键点。
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