PDF(Pubmed)
Abstract：
The prevalence of autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) is increasing, with a tendency for co-occurrence. Some studies indicate a connection between atypical sensory processing and executive function. This study aims to explore the distinctive etiology of executive function deficits in children with ASD+ADHD by investigating the relationship between sensory processing and executive function, comparing children with ASD, ASD+ADHD, ADHD, and typically developing children (TD).
METHODS: Sensory Profile 2 (SP-2) and Behavior Rating Inventory of Executive Function 2 (BRIEF-2) were measured in 120 school-aged children. The results of the above scales were compared across these four groups, and correlation and regression analyses between BRIEF2 and SP2 were conducted.
RESULTS: Our research revealed varying levels of atypical sensory processing and executive function anomalies across the three neurodevelopmental disorder groups compared to the TD group. The ASD+ADHD group showed particularly significant differences. The heightened emotional problems observed in ASD+ADHD children may be associated with more prominent atypical sensory processing. Variance analysis of inhibitory function revealed differences between ASD+ADHD and ADHD children, suggesting distinct etiological mechanisms for attention issues between ASD+ADHD and ADHD.
CONCLUSIONS: ASD+ADHD represents a phenotype distinct from both ASD and ADHD. Special consideration should be given to interventions for children with ASD+ADHD. The results of this study may offer a new perspective on understanding the occurrence of ASD+ADHD and potential individualized intervention methods.
METHODS: Sensory Profile 2 (SP-2) and Behavior Rating Inventory of Executive Function 2 (BRIEF-2) were measured in 120 school-aged children. The results of the above scales were compared across these four groups, and correlation and regression analyses between BRIEF2 and SP2 were conducted.
RESULTS: Our research revealed varying levels of atypical sensory processing and executive function anomalies across the three neurodevelopmental disorder groups compared to the TD group. The ASD+ADHD group showed particularly significant differences. The heightened emotional problems observed in ASD+ADHD children may be associated with more prominent atypical sensory processing. Variance analysis of inhibitory function revealed differences between ASD+ADHD and ADHD children, suggesting distinct etiological mechanisms for attention issues between ASD+ADHD and ADHD.
CONCLUSIONS: ASD+ADHD represents a phenotype distinct from both ASD and ADHD. Special consideration should be given to interventions for children with ASD+ADHD. The results of this study may offer a new perspective on understanding the occurrence of ASD+ADHD and potential individualized intervention methods.
摘要：
自闭症谱系障碍（ASD）和注意力缺陷/多动障碍（ADHD）的患病率正在增加，有共同发生的趋势。一些研究表明，非典型的感觉处理和执行功能之间存在联系。本研究旨在通过探讨感觉加工与执行功能的关系,探讨ASD+ADHD儿童执行功能缺陷的独特病因。将儿童与ASD进行比较，ASD+多动症,多动症,通常是发育中的儿童（TD）。
方法：在120名学龄儿童中测量了感官概况2（SP-2）和行为评估量表2（BRIEF-2）。以上量表的结果在这四组中进行了比较，并对BRIEF2和SP2进行了相关和回归分析。
结果：我们的研究显示，与TD组相比，三个神经发育障碍组的非典型感觉加工和执行功能异常水平不同。ASD+ADHD组表现出特别显著的差异。在ASDADHD儿童中观察到的情绪问题加剧可能与更突出的非典型感觉处理有关。抑制功能的方差分析显示ASD+ADHD和ADHD儿童之间存在差异，提示ASD+ADHD和ADHD之间注意力问题的不同病因机制。
结论：ASD+ADHD代表一种不同于ASD和ADHD的表型。应特别考虑对ASD+ADHD儿童的干预措施。这项研究的结果可能为理解ASDADHD的发生和潜在的个性化干预方法提供新的视角。
方法：在120名学龄儿童中测量了感官概况2（SP-2）和行为评估量表2（BRIEF-2）。以上量表的结果在这四组中进行了比较，并对BRIEF2和SP2进行了相关和回归分析。
结果：我们的研究显示，与TD组相比，三个神经发育障碍组的非典型感觉加工和执行功能异常水平不同。ASD+ADHD组表现出特别显著的差异。在ASDADHD儿童中观察到的情绪问题加剧可能与更突出的非典型感觉处理有关。抑制功能的方差分析显示ASD+ADHD和ADHD儿童之间存在差异，提示ASD+ADHD和ADHD之间注意力问题的不同病因机制。
结论：ASD+ADHD代表一种不同于ASD和ADHD的表型。应特别考虑对ASD+ADHD儿童的干预措施。这项研究的结果可能为理解ASDADHD的发生和潜在的个性化干预方法提供新的视角。
