关键词: adhesive bioactive materials hydrogel movable parts wound healing

Mesh : Wound Healing Humans Hydrogels / chemistry Bandages Animals Anti-Bacterial Agents / therapeutic use Skin / injuries

来  源:   DOI:10.3390/ijms25126610   PDF(Pubmed)

Abstract:
Skin is the largest organ in the human body and requires proper dressing to facilitate healing after an injury. Wounds on movable parts, such as the elbow, knee, wrist, and neck, usually undergo delayed and inefficient healing due to frequent movements. To better accommodate movable wounds, a variety of functional hydrogels have been successfully developed and used as flexible wound dressings. On the one hand, the mechanical properties, such as adhesion, stretchability, and self-healing, make these hydrogels suitable for mobile wounds and promote the healing process; on the other hand, the bioactivities, such as antibacterial and antioxidant performance, could further accelerate the wound healing process. In this review, we focus on the recent advances in hydrogel-based movable wound dressings and propose the challenges and perspectives of such dressings.
摘要:
皮肤是人体中最大的器官,需要适当的敷料以促进受伤后的愈合。可移动部件上的伤口,比如肘部,膝盖,手腕,脖子,通常经历延迟和低效的愈合由于频繁的运动。为了更好地适应可移动的伤口,已经成功开发了多种功能性水凝胶并将其用作柔性伤口敷料。一方面,机械性能,如附着力,可拉伸性,和自我修复,使这些水凝胶适用于移动伤口并促进愈合过程;另一方面,生物活动,如抗菌和抗氧化性能,可以进一步加速伤口愈合过程。在这次审查中,我们专注于基于水凝胶的可移动伤口敷料的最新进展,并提出了这种敷料的挑战和观点。
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