PDF(Pubmed)
Abstract：
We aimed to report sexual and reproductive outcomes following post-chemotherapy robot-assisted retroperitoneal unilateral lymph node dissection (PC-rRPLND) for non-seminomatous germ cell tumors (NSGCTs) at a high-volume cancer center. We collected records regarding sexual and reproductive outcomes of patients undergoing unilateral PC-rRPLND for stage II NSGCTs from January 2018 to November 2021. Preoperative and postoperative (at 12 months) ejaculatory function as well as erectile function, based on the International Index of Erectile Function-5 (IIEF-5) and Erection Hardness Score (EHS), were assessed. Only patients with a pre-operative IIEF-5 of ≥22 and EHS of ≥3 were included in this analysis. Overall, 22 patients undergoing unilateral PC-rRPLND met the inclusion criteria. Of these, seven (31.8%) patients presented an andrological disorder of any type after PC-rRPLND. Specifically, retrograde ejaculation was present in three (13.6%) patients and hypospermia was present in one (4.5%) patient. Moreover, three (13.6%) patients yielded erectile dysfunction (IIEF-5 < 22 and/or EHS < 3). Lastly, two (9.1%) succeeded in naturally conceiving a child after PC-rRPLND. Retrograde ejaculation is confirmed to be one of the most common complications of PC-rRPLND. Moreover, a non-negligible number of patients experience erectile dysfunction.
摘要：
我们的目的是报告化疗后机器人辅助腹膜后单侧淋巴结清扫术（PC-rRPLND）治疗非精原细胞生殖细胞肿瘤（NSGCT）后的性和生殖结果。我们收集了2018年1月至2021年11月在II期NSGCT中接受单侧PC-rRPLND的患者的性和生殖结局的记录。术前和术后（12个月时）射精功能以及勃起功能，根据国际勃起功能指数-5(IIEF-5)和勃起硬度评分(EHS)，被评估。本分析仅包括术前IIEF-5≥22和EHS≥3的患者。总的来说,22例接受单侧PC-rRPLND的患者符合纳入标准。其中,7例(31.8%)患者在PC-rRPLND后出现任何类型的男性疾病.具体来说,3例(13.6%)患者出现逆行射精,1例(4.5%)患者出现精子症.此外，3例（13.6%）患者出现勃起功能障碍（IIEF-5<22和/或EHS<3）。最后,两名（9.1％）在PC-rRPLND后成功自然怀孕。逆行射精被证实是PC-rRPLND最常见的并发症之一。此外，一个不可忽视的数量的患者经历勃起功能障碍。
