PDF(Pubmed)
Abstract：
Cartilage degeneration is a characteristic of osteoarthritis (OA), which is often observed in aging populations. This degeneration is due to the breakdown of articular cartilage (AC) mechanical and tribological properties primarily attributed to lubrication failure. Understanding the reasons behind these failures and identifying potential solutions could have significant economic and societal implications, ultimately enhancing quality of life. This review provides an overview of developments in the field of AC, focusing on its mechanical and tribological properties. The emphasis is on the role of lubrication in degraded AC, offering insights into its structure and function relationship. Further, it explores the fundamental connection between AC mechano-tribological properties and the advancement of its degradation and puts forth recommendations for strategies to boost its lubrication efficiency.
摘要：
软骨变性是骨关节炎（OA）的特征，这在老龄化人群中经常观察到。这种退化是由于主要归因于润滑失败的关节软骨(AC)机械和摩擦学特性的破坏。了解这些失败背后的原因并确定潜在的解决方案可能会产生重大的经济和社会影响。最终提高生活质量。这篇综述概述了AC领域的发展，专注于其力学和摩擦学性能。重点是润滑在退化AC中的作用，提供对其结构和功能关系的见解。Further,它探讨了交流机械摩擦学性能与降解进展之间的基本联系，并提出了提高其润滑效率的策略建议。
