PDF(Pubmed)
Abstract：
The umbilical or L3 vertebral body level is often used for body fat quantification using computed tomography. To explore the feasibility of using clinically acquired pelvic magnetic resonance imaging (MRI) for visceral fat measurement, we examined the correlation of visceral fat parameters at the umbilical and L5 vertebral body levels. We retrospectively analyzed T2-weighted half-Fourier acquisition single-shot turbo spin echo (HASTE) MR axial images from Crohn\'s disease patients who underwent MRI enterography of the abdomen and pelvis over a three-year period. We determined the area/volume of subcutaneous and visceral fat from the umbilical and L5 levels and calculated the visceral fat ratio (VFR = visceral fat/subcutaneous fat) and visceral fat index (VFI = visceral fat/total fat). Statistical analyses involved correlation analysis between both levels, inter-rater analysis between two investigators, and inter-platform analysis between two image-analysis platforms. Correlational analysis of 32 patients yielded significant associations for VFI (r = 0.85; p < 0.0001) and VFR (r = 0.74; p < 0.0001). Intraclass coefficients for VFI and VFR were 0.846 and 0.875 (good agreement) between investigators and 0.831 and 0.728 (good and moderate agreement) between platforms. Our study suggests that the L5 level on clinically acquired pelvic MRIs may serve as a reference point for visceral fat quantification.
摘要：
脐带或L3椎体水平通常用于使用计算机断层扫描对身体脂肪进行定量。探讨利用临床获得的盆腔磁共振成像（MRI）测量内脏脂肪的可行性，我们检查了脐部和L5椎体水平的内脏脂肪参数的相关性。我们回顾性分析了在三年内接受腹部和骨盆MRI小肠造影的克罗恩病患者的T2加权半傅立叶采集单发涡轮自旋回波（HASTE）MR轴向图像。我们从脐带和L5水平确定皮下和内脏脂肪的面积/体积，并计算内脏脂肪比率（VFR=内脏脂肪/皮下脂肪）和内脏脂肪指数（VFI=内脏脂肪/总脂肪）。统计分析涉及两个水平之间的相关性分析，两名调查人员之间的评估者间分析，以及两个图像分析平台之间的平台间分析。32例患者的相关性分析得出VFI（r=0.85；p<0.0001）和VFR（r=0.74；p<0.0001）的显著相关性。研究人员之间的VFI和VFR的组内系数分别为0.846和0.875（良好的一致性），平台之间为0.831和0.728（良好和中等的一致性）。我们的研究表明，临床上获得的盆腔MRI的L5水平可以作为内脏脂肪定量的参考点。
