PDF(Pubmed)
Abstract：
The consequences of COVID-19 constitute a significant burden to healthcare systems worldwide. Conducting an HRQoL assessment is an important aspect of the evaluation of the impact of the disease. The aim of this study was to investigate the prevalence of persistent symptoms and their impact on HRQoL and health status in COVID-19 convalescents. The study group consists of 46 patients who required hospitalization due to respiratory failure and who were subsequently evaluated 3 and 9 months after hospital discharge. At the follow-up visits, the patients were asked to assess their HRQoL using the EQ-5D-5L questionnaire. The results of chest CT, 6MWT, as well as the severity of the course of COVID-19 were also considered in the analysis. The obtained results have identified fatigue as the most common persistent symptom. The majority of the convalescents reported an impairment of HRQoL in at least one domain (80% and 82% after 3 and 9 months, respectively), of which the most common was that of pain/discomfort. The presence of ongoing symptoms may affect HRQoL in particular domains. The 6MWT outcome correlates with HRQoL 3 months after hospital discharge. Therefore, it may be useful in identifying patients with reduced HRQoL, allowing early interventions aimed at its improvement.
摘要：
COVID-19的后果对全球医疗保健系统构成了重大负担。进行HRQoL评估是评估疾病影响的重要方面。这项研究的目的是调查COVID-19疗养者中持续症状的患病率及其对HRQoL和健康状况的影响。研究组由46例因呼吸衰竭而需要住院治疗的患者组成，随后在出院后3和9个月进行评估。在后续访问中，患者被要求使用EQ-5D-5L问卷评估他们的HRQoL.胸部CT的结果,6MWT,分析中还考虑了COVID-19病程的严重程度。获得的结果确定疲劳是最常见的持续症状。大多数康复患者报告至少一个领域的HRQoL受损（3个月和9个月后分别为80％和82％，分别)，其中最常见的是疼痛/不适。持续症状的存在可能会影响特定领域的HRQoL。6MWT结果与出院后3个月的HRQoL相关。因此,它可能有助于识别HRQoL降低的患者，允许早期干预旨在改善它。
