PDF(Pubmed)
Abstract：
BACKGROUND: Chronic low back pain (CLBP) is a frequent disease. It is a critical health concern that can influence functional capacity by restricting living activities.
OBJECTIVE: The current study is to investigate the effects of transcutaneous vagus nerve stimulation (TVNs) in the management of CLBP.
METHODS: We searched the databases on Google Scholar, PubMed, Web of Science, Cochrane, and Pedro for randomized clinical trial (RCT) studies published in any language that looked at the effectiveness of TVNs in people with chronic LBP. The inclusion criteria were PICO. Participants in the research were people (≥ 18 years) diagnosed with persistent low back pain for more than 3 months. Study quality was assessed using Cochrane ROB 2.
RESULTS: Our database search found 1084 RCT. A number of studies that were not necessary for the issue were removed, and the overall outcome was six trials. Risk of bias (ROB) evaluations at the study level (derived from outcomes) are reported. In the six studies, two (33.3%) had an overall uncertain ROB (i.e., some concerns), whereas one (16.7%) had a high overall ROB. Three trials (50%) had a low overall RoB.
CONCLUSIONS: There is still no evidence to support the use of transcutaneous vagus nerve stimulation as a viable therapeutic rehabilitation strategy. Therefore, we recommend high-quality trials and long-term follow-up to evaluate disability, quality of life, and pain outcomes in these patients.
OBJECTIVE: The current study is to investigate the effects of transcutaneous vagus nerve stimulation (TVNs) in the management of CLBP.
METHODS: We searched the databases on Google Scholar, PubMed, Web of Science, Cochrane, and Pedro for randomized clinical trial (RCT) studies published in any language that looked at the effectiveness of TVNs in people with chronic LBP. The inclusion criteria were PICO. Participants in the research were people (≥ 18 years) diagnosed with persistent low back pain for more than 3 months. Study quality was assessed using Cochrane ROB 2.
RESULTS: Our database search found 1084 RCT. A number of studies that were not necessary for the issue were removed, and the overall outcome was six trials. Risk of bias (ROB) evaluations at the study level (derived from outcomes) are reported. In the six studies, two (33.3%) had an overall uncertain ROB (i.e., some concerns), whereas one (16.7%) had a high overall ROB. Three trials (50%) had a low overall RoB.
CONCLUSIONS: There is still no evidence to support the use of transcutaneous vagus nerve stimulation as a viable therapeutic rehabilitation strategy. Therefore, we recommend high-quality trials and long-term follow-up to evaluate disability, quality of life, and pain outcomes in these patients.
摘要：
背景：慢性下腰痛（CLBP）是一种常见的疾病。这是一个关键的健康问题，可以通过限制生活活动来影响功能能力。
目的：本研究旨在探讨经皮迷走神经刺激（TVNs）在CLBP治疗中的作用。
方法：我们搜索了GoogleScholar上的数据库，PubMed,WebofScience,科克伦,和Pedro用于以任何语言发表的随机临床试验（RCT）研究，这些研究着眼于TVN在慢性LBP患者中的有效性。纳入标准为PICO。该研究的参与者是被诊断为持续下腰痛超过3个月的人（≥18岁）。使用CochraneROB2评估研究质量。
结果：我们的数据库搜索找到了1084RCT。删除了一些不必要的研究，总体结局为6项试验.报告了研究水平（来自结果）的偏倚风险（ROB）评估。在六项研究中，两个(33.3%)的总体ROB不确定(即，一些担忧)，而1人(16.7%)的总体ROB较高。三项试验(50%)具有较低的总体RoB。
结论：仍然没有证据支持使用经皮迷走神经刺激作为一种可行的治疗性康复策略。因此,我们推荐高质量的试验和长期随访来评估残疾，生活质量,以及这些患者的疼痛结果。
目的：本研究旨在探讨经皮迷走神经刺激（TVNs）在CLBP治疗中的作用。
方法：我们搜索了GoogleScholar上的数据库，PubMed,WebofScience,科克伦,和Pedro用于以任何语言发表的随机临床试验（RCT）研究，这些研究着眼于TVN在慢性LBP患者中的有效性。纳入标准为PICO。该研究的参与者是被诊断为持续下腰痛超过3个月的人（≥18岁）。使用CochraneROB2评估研究质量。
结果：我们的数据库搜索找到了1084RCT。删除了一些不必要的研究，总体结局为6项试验.报告了研究水平（来自结果）的偏倚风险（ROB）评估。在六项研究中，两个(33.3%)的总体ROB不确定(即，一些担忧)，而1人(16.7%)的总体ROB较高。三项试验(50%)具有较低的总体RoB。
结论：仍然没有证据支持使用经皮迷走神经刺激作为一种可行的治疗性康复策略。因此,我们推荐高质量的试验和长期随访来评估残疾，生活质量,以及这些患者的疼痛结果。
