关键词: Adult intensive care Intensive care Nutrition and metabolism Nutritional support Vitamins and supplements

Mesh : Humans Extracorporeal Membrane Oxygenation / adverse effects methods Ascorbic Acid Deficiency / complications Male Hemorrhage / etiology therapy Ascorbic Acid / therapeutic use Female Middle Aged Mucous Membrane

来  源:   DOI:10.1136/bcr-2023-259185

Abstract:
A major complication with extracorporeal membrane oxygenation (ECMO) is bleeding which can occur in up to 40% of cases and can be life-threatening. Minor bleeding may be overlooked and under-reported. While some of the underlying mechanisms such as platelet injury and anticoagulation therapy have been identified, several other factors are still under-researched. Here, we describe a unique case of a subtle mucosal membrane bleeding that is found to be associated with vitamin C deficiency while on treatment with ECMO. Investigating vitamin C levels may be useful in understanding causes of bleeding in some patients on ECMO therapy, particularly if there are risk factors for malnutrition.
摘要:
体外膜氧合(ECMO)的主要并发症是出血,最多可发生40%的病例,可能危及生命。轻微出血可能被忽视和报告不足。虽然已经确定了一些潜在的机制,如血小板损伤和抗凝治疗,其他几个因素仍未得到充分研究。这里,我们描述了一个独特的病例,即在接受ECMO治疗时发现与维生素C缺乏相关的细微粘膜出血.调查维生素C水平可能有助于了解一些接受ECMO治疗的患者出血的原因。特别是如果有营养不良的危险因素。
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