关键词: Chemotherapy Inguinal lymph nodes Metastases Multidisciplinary care Pelvic lymph nodes Penile cancer Radiation therapy Squamous cell carcinoma

Mesh : Humans Lymphatic Metastasis Inguinal Canal Male Penile Neoplasms / therapy pathology Lymph Node Excision Lymph Nodes / pathology Pelvis Neoplasm Staging

来  源:   DOI:10.1016/j.ucl.2024.03.012

Abstract:
Penile cancer with bulky inguinal metastasis has a high probability of harboring pathologically involved lymph nodes best managed in a multidisciplinary care setting. Appropriate staging with cross-sectional imaging and fine-needle aspirate cytology of suspicious nodes guide decision-making for the use of platinum-based neoadjuvant chemotherapy followed by inguinal lymph node dissection. Surgical resection plays an important diagnostic, therapeutic, and guiding role in disease management. Patients with adverse pathologic features, especially those with extranodal disease extension, may derive additional benefit from adjuvant radiotherapy.
摘要:
具有大腹股沟转移的阴茎癌具有很高的可能性,在多学科护理环境中最好地治疗病理累及的淋巴结。对可疑淋巴结进行横断面成像和细针抽吸细胞学检查,以适当的分期指导决策,以使用基于铂的新辅助化疗,然后进行腹股沟淋巴结清扫。手术切除起着重要的诊断,治疗性的,以及在疾病管理中的指导作用。具有不良病理特征的患者,尤其是那些患有结外疾病的人,可能从辅助放疗中获得额外的益处。
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