关键词: Haematology (incl blood transfusion) Pleural infection Respiratory medicine

Mesh : Humans Multiple Myeloma / complications diagnosis Female Pleural Effusion, Malignant / etiology diagnosis diagnostic imaging Middle Aged Aged Pleural Effusion / etiology diagnosis

来  源:   DOI:10.1136/bcr-2023-258935

Abstract:
Multiple myeloma is a rare haematological malignancy characterised by the clonal proliferation of plasma cells within the bone marrow. Typical manifestations include bone pain, fatigue and monoclonal protein elevation in serum and urine. Less than 1% of cases develop myelomatous pleural effusion, a severe complication indicative of advanced disease and a very poor prognosis.Here, we present a case of a woman with a new diagnosis of multiple myeloma complicated by bilateral myelomatous pleural effusions as the initial presentation. This case underscores the diverse clinical spectrum of multiple myeloma, the significance of timely diagnosis and the threatening implications associated with myelomatous pleural effusions.
摘要:
多发性骨髓瘤是一种罕见的血液恶性肿瘤,其特征是骨髓内浆细胞的克隆增殖。典型的表现包括骨痛,血清和尿液中的疲劳和单克隆蛋白升高。少于1%的病例出现骨髓瘤性胸腔积液,严重的并发症表明晚期疾病和非常差的预后。这里,我们介绍了一个新诊断为多发性骨髓瘤并伴有双侧骨髓瘤性胸腔积液的女性病例。这个病例强调了多发性骨髓瘤的不同临床谱,及时诊断的意义和与骨髓瘤性胸腔积液相关的威胁意义。
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