评论 : 表达肿瘤靶向免疫细胞因子 IL - 12 的间皮素 CAR - T 细胞产生持久的疗效和较少的副作用。
关键词: CAR-T cell therapy Combination treatment IL-12 Mesothelin Tumor antigen epitope
Mesh : Humans Interleukin-12 Mesothelin GPI-Linked Proteins / immunology metabolism antagonists & inhibitors Immunotherapy, Adoptive / methods adverse effects Receptors, Chimeric Antigen / immunology metabolism Neoplasms / immunology therapy Animals
来 源: DOI:10.1016/j.phrs.2024.107267