Abstract：
Mammary analogue secretory carcinoma (MASC) is a rare salivary gland tumor which shares its histologic, immunohistochemical, and genetic features with the secretory carcinoma (SC) of breast. In this case report, we describe a case of MASC in a young adolescent male with swelling in the right angle of mandible which is a relatively rare site to present along with its correlation of cytological, histological, and immunohistochemical features. A 16-year-old male came with the complaint of swelling in the right angle of mandible since 2 years. Contrast-enhanced computed tomography (CECT) neck revealed differential diagnosis of nerve sheath tumor, pleomorphic adenoma, and adenoid cystic neoplasm was kept, and subsequently fine-needle aspiration cytology (FNAC) was done. FNAC was done in which differential diagnosis of myoepithelial neoplasm, acinic cell carcinoma, and SC was given. Surgical excision was done followed by histopathological examination. Immunohistochemistry panel was also applied, and final diagnosis of SC was rendered. SC has distinct cytological, histological, and immunohistochemical features which should be recognized by the pathologists for the appropriate management of the patient.
摘要：
乳腺类似物分泌癌（MASC）是一种罕见的唾液腺肿瘤，具有相同的组织学特征，免疫组织化学，乳腺分泌性癌（SC）的遗传特征。在这个案例报告中,我们描述了一个年轻的青少年男性MASC病例，下颌骨直角肿胀，这是一个相对罕见的部位，组织学,和免疫组织化学特征。一名16岁的男性自2年以来一直抱怨下颌骨直角肿胀。对比增强计算机断层扫描（CECT）颈部显示神经鞘瘤的鉴别诊断，多形性腺瘤，腺样囊性肿瘤保留，随后进行细针穿刺细胞学检查(FNAC).进行FNAC，其中肌上皮肿瘤的鉴别诊断，腺泡细胞癌，SC被给予。进行手术切除，然后进行组织病理学检查。还应用了免疫组织化学小组，最终诊断为SC。SC具有独特的细胞学，组织学,和免疫组织化学特征，病理学家应识别这些特征，以便对患者进行适当的管理。
